Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.39 |
| ▸ | NLN | Q9BYT8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 3/20 | 0.38 |
| ▸ | MC3R | P41968 | 3/20 | 0.38 |
| ▸ | MC1R | Q01726 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CTSV | O60911 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | FCER2 | P06734 | 2/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12718130 | 0.83 | NPC1 (0.47) | LMNAHPGDCTSVCTSLGABRA1 | |
| SCHEMBL5557678 | 0.78 | HTR2A (0.57) | NLNMC4RMC3RMC1RFCER2 | |
| SCHEMBL5966495 | 0.78 | HTR2A (0.57) | NLNMC4RMC3RMC1RFCER2 | |
| SCHEMBL17189671 | 0.77 | KMT2A (0.51) | MAOAP2RY12LMNAHPGDCTSV | |
| Hydrochloric Acid SCHEMBL5556491 | 0.77 | HTR2A (0.55) | NLNMC4RMC3RMC1RFCER2 | |
| SCHEMBL30107598 | 0.75 | MEN1 (0.51) | MAOAP2RY12LMNAHPGDCTSV | |
| SCHEMBL26793178 | 0.75 | MEN1 (0.51) | MAOAP2RY12LMNAHPGDCTSV | |
| SCHEMBL21690442 | 0.75 | MEN1 (0.51) | MAOAP2RY12LMNAHPGDCTSV | |
| SCHEMBL12718134 | 0.72 | PTPN1 (0.54) | CTSL | |
| SCHEMBL22875997 | 0.70 | PDE3B (0.58) | MAOALMNAHPGDCTSVCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969773-B2 | Polymers, pharmaceutical compositions and methods of synthesizing the same | NEW YORK UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |
| US-9969773-B2 | Polymers, pharmaceutical compositions and methods of synthesizing the same | NEW YORK UNIVERSITY (US) | 2018-05-15 | — | — | US | disclosed |
| US-20150299254-A1 | NOVEL POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME | NEW YORK UNIVERSITY | 2015-10-22 | — | — | US | disclosed |
| US-20150299254-A1 | NOVEL POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME | NEW YORK UNIVERSITY | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299254-A1 | NOVEL POLYMERS, PHARMACEUTICAL COMPOSITIONS AND METHODS OF SYNTHESIZING THE SAME | PAICS, F12, CYP2C19 | MAOA 146/4885P2RY12 1651/4885PRCP 460/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.