Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.82 |
| ▸ | TSHR | P16473 | 1/20 | 0.82 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.82 |
| ▸ | CASP1 | P29466 | 1/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.57 |
| ▸ | FUBP1 | Q96AE4 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4203865 | 0.91 | MAPT (1.00) | MAPTTSHRMAPK1CASP1ALDH1A1 | |
| Benzylamine SCHEMBL1719112 | 0.85 | KDM4E (0.67) | MAPTTSHRMAPK1CASP1ALDH1A1 | |
| SCHEMBL1717548 | 0.85 | MAPT (0.76) | MAPTTSHRMAPK1CASP1ALDH1A1 | |
| SCHEMBL1718989 | 0.83 | MAPT (0.75) | MAPTTSHRMAPK1CASP1ALDH1A1 | |
| Benzylamine SCHEMBL1719919 | 0.83 | KDM4E (0.72) | MAPTTSHRMAPK1CASP1ALDH1A1 | |
| SCHEMBL17066247 | 0.83 | MAPT (1.00) | MAPTTSHRMAPK1CASP1ALDH1A1 | |
| SCHEMBL1718145 | 0.82 | MAPT (0.77) | MAPTTSHRMAPK1CASP1ALDH1A1 | |
| SCHEMBL17297256 | 0.80 | THRB (0.69) | MAPTTSHRMAPK1CASP1ALDH1A1 | |
| Benzylamine SCHEMBL1719060 | 0.79 | KDM4E (0.63) | MAPTTSHRMAPK1CASP1ALDH1A1 | |
| SCHEMBL1719728 | 0.79 | MAPT (0.80) | MAPTTSHRMAPK1CASP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |