SCHEMBL17194374

SCHEMBL17194374

Cc1ncn(-c2sc3c(c2C#N)CCN(C(=O)OC(C)(C)C)C3)n1

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 2/20 0.47
▸ MAPT P10636 2/20 0.47
▸ GAA P10253 1/20 0.47
▸ P2RX3 P56373 12/20 0.46
▸ ADORA1 P30542 2/20 0.45
▸ MKNK1 Q9BUB5 3/20 0.42
▸ BPTF Q12830 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17194373 0.83 ADORA1 (0.48) KDM4EMAPTP2RX3ADORA1MKNK1
SCHEMBL17194353 0.80 ADORA1 (0.50) KDM4EMAPTGAAP2RX3ADORA1
SCHEMBL17194169 0.77 L3MBTL1 (0.52) KDM4EMAPTGAAADORA1MKNK1
SCHEMBL20922384 0.76 ADORA1 (0.55) KDM4EMAPTGAAP2RX3ADORA1
SCHEMBL17194176 0.76 ADORA1 (0.55) KDM4EMAPTGAAP2RX3ADORA1
SCHEMBL17194311 0.76 ADORA1 (0.55) KDM4EMAPTGAAP2RX3ADORA1
SCHEMBL2643671 0.76 MAPT (0.73) KDM4EMAPTGAAADORA1MKNK1
SCHEMBL4510907 0.75 ADORA1 (0.45) KDM4EMAPTGAAP2RX3ADORA1
SCHEMBL17194296 0.74 ADORA1 (0.53) KDM4EMAPTGAAP2RX3ADORA1
SCHEMBL13473579 0.74 P2RX3 (0.54) P2RX3MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131890-B1 COMPOUNDS FOR TREATING VIRAL INFECTIONS PASTEUR INSTITUT KOREA (KR) 2019-04-24 — — EP disclosed
US-9809602-B2 Compounds for treating viral infections INSTITUT PASTEUR KOREA (KR) 2017-11-07 — — US disclosed
US-20170044181-A1 COMPOUNDS FOR TREATING VIRAL INFECTIONS INSTITUT PASTEUR KOREA (KR) 2017-02-16 — — US disclosed
WO-2015158908-A1 COMPOUNDS FOR TREATING VIRAL INFECTIONS INSTITUT PASTEUR KOREA (KR) 2015-10-22 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044181-A1 COMPOUNDS FOR TREATING VIRAL INFECTIONS HAVCR2, MAVS, EIF2AK2 KDM4E 4004/4885MAPT 2197/4885GAA 77/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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