SCHEMBL17195063

SCHEMBL17195063

COc1ccc(C#Cc2ccc3c4c(cccc24)C(=O)N(OS(=O)(=O)C(F)(F)F)C3=O)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KCNH2 Q12809 2/20 0.40
▸ KMT2A Q03164 6/20 0.39
▸ MEN1 O00255 4/20 0.39
▸ L3MBTL1 Q9Y468 3/20 0.39
▸ MAPT P10636 3/20 0.39
▸ POLB P06746 2/20 0.39
▸ VDR P11473 1/20 0.36
▸ PRMT1 Q99873 1/20 0.36
▸ PLK1 P53350 3/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ KDM4E B2RXH2 3/20 0.35
▸ HTT P42858 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ PABPC1 P11940 1/20 0.35
▸ XBP1 P17861 1/20 0.35
▸ NFKB1 P19838 1/20 0.35
▸ SMARCA2 P51531 1/20 0.35
▸ NFKB2 Q00653 1/20 0.35
▸ RELA Q04206 1/20 0.35
▸ HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17195065 0.90 KMT2A (0.41) KCNH2KMT2AMEN1L3MBTL1MAPT
SCHEMBL17185507 0.90 KMT2A (0.45) KMT2AMEN1L3MBTL1MAPTPOLB
SCHEMBL17195066 0.83 KMT2A (0.39) KMT2AMEN1L3MBTL1MAPTPOLB
SCHEMBL12296926 0.80 KMT2A (0.40) KMT2AMEN1L3MBTL1MAPTPOLB
SCHEMBL18069192 0.79 KMT2A (0.46) KMT2AMEN1L3MBTL1MAPTPOLB
SCHEMBL18071775 0.78 KMT2A (0.40) KMT2AMEN1L3MBTL1MAPTPOLB
SCHEMBL18069178 0.78 MEN1 (0.39) KCNH2KMT2AMEN1L3MBTL1MAPT
SCHEMBL18069161 0.77 KMT2A (0.42) KMT2AMEN1L3MBTL1MAPTPOLB
SCHEMBL18069167 0.77 TDP1 (0.39) KMT2AMEN1L3MBTL1MAPTPOLB
SCHEMBL18069176 0.77 KMT2A (0.41) KMT2AMEN1L3MBTL1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9505721-B2 Aromatic imide compound and method for producing same AZ ELECRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-11-29 — — US disclosed
US-9505721-B2 Aromatic imide compound and method for producing same AZ ELECRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-11-29 — — US disclosed
US-20150299132-A1 AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2015-10-22 — — US disclosed
US-20150299132-A1 AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2015-10-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150299132-A1 AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME H1-0, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRH4 KCNH2 106/4885KMT2A 753/4885MEN1 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback