SCHEMBL17185507

SCHEMBL17185507

O=C1c2cccc3c(C#Cc4ccccc4)ccc(c23)C(=O)N1OS(=O)(=O)C(F)(F)F

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 9/20 0.45
▸ MAPT P10636 6/20 0.45
▸ MEN1 O00255 6/20 0.45
▸ POLB P06746 2/20 0.45
▸ L3MBTL1 Q9Y468 2/20 0.45
▸ ALDH1A1 P00352 8/20 0.41
▸ KDM4E B2RXH2 7/20 0.41
▸ HPGD P15428 5/20 0.41
▸ HTT P42858 3/20 0.41
▸ BRD4 O60885 1/20 0.35
▸ USP2 O75604 4/20 0.34
▸ LMNA P02545 2/20 0.34
▸ KEAP1 Q14145 2/20 0.34
▸ NFE2L2 Q16236 2/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ THRB P10828 1/20 0.34
▸ CDC14B O60729 1/20 0.34
▸ CDC14A Q9UNH5 1/20 0.34
▸ RECQL P46063 2/20 0.33
▸ GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17195065 0.92 KMT2A (0.41) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL17195066 0.91 KMT2A (0.39) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL17195063 0.90 KCNH2 (0.40) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18069192 0.86 KMT2A (0.46) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18071775 0.84 KMT2A (0.40) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL12296926 0.83 KMT2A (0.40) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18576631 0.81 MEN1 (0.34) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18069178 0.81 MEN1 (0.39) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18069161 0.80 KMT2A (0.42) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18071768 0.80 MAPT (0.42) KMT2AMAPTMEN1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10976658-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications HERAEUS EPURIO LLC (US) 2021-04-13 — — US disclosed
US-9709886-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2017-07-18 — — US disclosed
US-9709886-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2017-07-18 — — US disclosed
WO-2017034814-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS Heraeus Precious Metals North America Daychem LLC (US) 2017-03-02 — — WO disclosed
US-20170003587-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2017-01-05 — — US disclosed
US-20170003587-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2017-01-05 — — US disclosed
US-9505721-B2 Aromatic imide compound and method for producing same AZ ELECRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-11-29 — — US disclosed
US-9505721-B2 Aromatic imide compound and method for producing same AZ ELECRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-11-29 — — US disclosed
US-9505721-B2 Aromatic imide compound and method for producing same AZ ELECRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (LU) 2016-11-29 — — US disclosed
US-9477150-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2016-10-25 — — US disclosed
WO-2016148809-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS Heraeus Precious Metals North America Daychem LLC (US) 2016-09-22 — — WO disclosed
US-20160266487-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2016-09-15 — — US disclosed
US-20160266487-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2016-09-15 — — US disclosed
US-9383644-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2016-07-05 — — US disclosed
US-9383644-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2016-07-05 — — US disclosed
US-20160085148-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2016-03-24 — — US disclosed
US-20160085148-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2016-03-24 — — US disclosed
US-20150299132-A1 AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2015-10-22 — — US disclosed
US-20150299132-A1 AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2015-10-22 — — US disclosed
US-20150299132-A1 AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME AZ ELECTRONIC MATERIALS (LUXEMBOURG) S.A.R.L. (US) 2015-10-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160266487-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS ALAD, MPST, ASIC1 KMT2A 1020/4885MAPT 3437/4885MEN1 1317/4885
US-20170003587-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS ALAD, MPST, ASIC1 KMT2A 1020/4885MAPT 3437/4885MEN1 1317/4885
US-10976658-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications ALAD, MPST, ASIC1 KMT2A 1474/4885MAPT 4221/4885MEN1 1810/4885
US-20150299132-A1 AROMATIC IMIDE COMPOUND AND METHOD FOR PRODUCING SAME H1-0, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, HRH4 KMT2A 753/4885MAPT 4416/4885MEN1 1882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback