SCHEMBL18069192

SCHEMBL18069192

CS(=O)(=O)ON1C(=O)c2cccc3c(C#Cc4ccccc4)ccc(c23)C1=O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KMT2A Q03164 11/20 0.46
▸ MAPT P10636 8/20 0.46
▸ MEN1 O00255 7/20 0.46
▸ POLB P06746 3/20 0.46
▸ L3MBTL1 Q9Y468 2/20 0.46
▸ ALDH1A1 P00352 11/20 0.42
▸ KDM4E B2RXH2 11/20 0.42
▸ HPGD P15428 8/20 0.42
▸ HTT P42858 4/20 0.42
▸ USP2 O75604 4/20 0.39
▸ KEAP1 Q14145 3/20 0.39
▸ NFE2L2 Q16236 3/20 0.39
▸ VDR P11473 1/20 0.36
▸ GAA P10253 1/20 0.36
▸ PRMT1 Q99873 1/20 0.36
▸ LMNA P02545 3/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ XBP1 P17861 2/20 0.35
▸ PABPC1 P11940 1/20 0.35
▸ NFKB1 P19838 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17185507 0.86 KMT2A (0.45) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18069174 0.82 KMT2A (0.41) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL15705346 0.81 KMT2A (0.40) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18069175 0.80 TDP1 (0.40) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL17195063 0.79 KCNH2 (0.40) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL17195065 0.79 KMT2A (0.41) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL17185506 0.78 MAPT (0.54) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18069205 0.78 KMT2A (0.42) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18069201 0.78 KMT2A (0.42) KMT2AMAPTMEN1POLBL3MBTL1
SCHEMBL18069183 0.78 TDP1 (0.39) KMT2AMAPTMEN1POLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9709886-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2017-07-18 — — US disclosed
US-20170003587-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2017-01-05 — — US disclosed
US-9477150-B2 Sulfonic acid derivative compounds as photoacid generators in resist applications Heraeus Precious Metals North America Daychem LLC (US) 2016-10-25 — — US disclosed
US-20160266487-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS HERAEUS EPURIO LLC 2016-09-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160266487-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS ALAD, MPST, ASIC1 KMT2A 1020/4885MAPT 3437/4885MEN1 1317/4885
US-20170003587-A1 SULFONIC ACID DERIVATIVE COMPOUNDS AS PHOTOACID GENERATORS IN RESIST APPLICATIONS ALAD, MPST, ASIC1 KMT2A 1020/4885MAPT 3437/4885MEN1 1317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback