Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9313874 | 0.88 | L3MBTL1 (0.76) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10973039 | 0.82 | L3MBTL1 (0.63) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10201970 | 0.82 | NPC1 (0.63) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL12376621 | 0.81 | POLB (0.75) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL15946355 | 0.81 | RAB9A (0.72) | ALDH1A1MEN1KMT2ASMN1; SMN2RAB9A | |
| SCHEMBL14817492 | 0.81 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL12125403 | 0.80 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL13342363 | 0.80 | ALDH1A1 (0.56) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL10201967 | 0.80 | MAPT (0.56) | L3MBTL1ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL1117828 | 0.80 | L3MBTL1 (0.69) | L3MBTL1ALDH1A1HTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426108-A1 | Processes and intermediates for preparing fused heterocyclic kinase inhibitors | MethylGene Inc. (CA) | 2012-03-07 | — | — | EP | disclosed |