Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 3/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 3/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29273199 | 0.88 | NQO2 (0.55) | NQO2ERCC5FEN1KIF11ALDH1A1 | |
| SCHEMBL14138088 | 0.88 | NQO2 (0.57) | NQO2ERCC5FEN1KIF11ALDH1A1 | |
| SCHEMBL15828182 | 0.87 | NPC1 (0.53) | ALDH1A1MAPTPTPN2PTPN1KDM4E | |
| SCHEMBL23744356 | 0.86 | NQO2 (0.54) | NQO2ERCC5FEN1KIF11ALDH1A1 | |
| SCHEMBL19585564 | 0.79 | DHODH (0.56) | KIF11DHODHASIC1ALDH1A1MAPT | |
| SCHEMBL14179913 | 0.78 | SMN1; SMN2 (0.46) | NQO2PDE4AALDH1A1MAPTKDM4E | |
| SCHEMBL24798384 | 0.77 | CYP2E1 (0.56) | NQO2ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL29083928 | 0.76 | ALOX15 (0.57) | KIF11ALDH1A1MAPTPTPN2PTPN1 | |
| SCHEMBL12632448 | 0.76 | NQO2 (0.47) | NQO2ERCC5FEN1KIF11ALDH1A1 | |
| SCHEMBL24089649 | 0.76 | NQO2 (0.47) | NQO2ERCC5FEN1KIF11PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150303397-A1 | INORGANIC BARRIER LAYERS | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-20150303397-A1 | INORGANIC BARRIER LAYERS | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |