SCHEMBL23744356

SCHEMBL23744356

CC(C)(C)c1ccc(-c2ccc(-c3ccc(-c4ccccc4)cc3)o2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 3/20 0.54
ERCC5 P28715 1/20 0.49
FEN1 P39748 1/20 0.49
KIF11 P52732 4/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
S1PR1 P21453 1/20 0.41
CYP2E1 P05181 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2A6 P11509 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2B6 P20813 1/20 0.41
CYP2C19 P33261 1/20 0.41
CYP1A2 P05177 1/20 0.41
CASP1 P29466 1/20 0.41
CASP7 P55210 1/20 0.41
HSD17B10 Q99714 1/20 0.41
EGFR P00533 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29273199 0.98 NQO2 (0.55) NQO2ERCC5FEN1KIF11ALDH1A1
SCHEMBL14138088 0.89 NQO2 (0.57) NQO2ERCC5FEN1KIF11ALDH1A1
SCHEMBL17196192 0.86 NQO2 (0.49) NQO2ERCC5FEN1KIF11ALDH1A1
SCHEMBL128222 0.85 KIF11 (0.59) KIF11ALDH1A1CYP2C9NPC1RAB9A
SCHEMBL3421942 0.85 KIF11 (0.59) KIF11ALDH1A1CYP2C9NPC1RAB9A
Ethane SCHEMBL27903947 0.83 KIF11 (0.57) KIF11ALDH1A1CYP2C9NPC1RAB9A
SCHEMBL4344550 0.82 ALDH1A1 (0.61) NQO2ALDH1A1HPGDCYP2E1CYP3A4
SCHEMBL4340657 0.82 ALDH1A1 (0.61) NQO2ALDH1A1HPGDCYP2E1CYP3A4
SCHEMBL28102065 0.79 DHODH (0.54) KIF11ALDH1A1CYP2C9
SCHEMBL18801808 0.79 KIF11 (0.53) KIF11ALDH1A1HPGDCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210249569-A1 LIGHT-EMITTING DEVICE NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2021-08-12 US disclosed