Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 4/20 | 0.55 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744356 | 0.98 | NQO2 (0.54) | NQO2ERCC5FEN1ALDH1A1HPGD | |
| SCHEMBL14138088 | 0.91 | NQO2 (0.57) | NQO2ERCC5FEN1ALDH1A1HPGD | |
| SCHEMBL17196192 | 0.88 | NQO2 (0.49) | NQO2ERCC5FEN1ALDH1A1KIF11 | |
| SCHEMBL128222 | 0.82 | KIF11 (0.59) | ALDH1A1KIF11CYP2C9NPC1RAB9A | |
| SCHEMBL3421942 | 0.82 | KIF11 (0.59) | ALDH1A1KIF11CYP2C9NPC1RAB9A | |
| Ethane SCHEMBL27903947 | 0.80 | KIF11 (0.57) | ALDH1A1KIF11CYP2C9NPC1RAB9A | |
| SCHEMBL4344550 | 0.79 | ALDH1A1 (0.61) | NQO2ALDH1A1HPGDCYP2E1CYP3A4 | |
| SCHEMBL4340657 | 0.79 | ALDH1A1 (0.61) | NQO2ALDH1A1HPGDCYP2E1CYP3A4 | |
| SCHEMBL12632448 | 0.79 | NQO2 (0.47) | NQO2ERCC5FEN1ALDH1A1HPGD | |
| SCHEMBL29273187 | 0.79 | KIF11 (0.68) | NQO2ALDH1A1HPGDKIF11CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791448-A | Anti-atopic dermatitis active furan compound, preparation and application thereof | 中国医学科学院药物研究所 | 2024-10-18 | — | — | CN | claimed |
| CN-118791448-A | Anti-atopic dermatitis active furan compound, preparation and application thereof | 中国医学科学院药物研究所 | 2024-10-18 | — | — | CN | disclosed |
| CN-118184606-A | Method for preparing 2, 5-disubstituted and 2,3, 5-trisubstituted furan skeleton derivative | 中国医学科学院药物研究所 | 2024-06-14 | — | — | CN | disclosed |