Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1718047 | 0.89 | RXFP1 (0.59) | RXFP1POLBMAPTAPOBEC3ACTDSP1 | |
| SCHEMBL1717917 | 0.85 | RXFP1 (0.72) | RXFP1POLBMAPTAPOBEC3AALDH1A1 | |
| SCHEMBL3282802 | 0.85 | RXFP1 (0.69) | RXFP1POLBMAPTAPOBEC3ACTDSP1 | |
| SCHEMBL1719687 | 0.84 | RXFP1 (0.67) | RXFP1POLBMAPTALDH1A1HSD17B10 | |
| SCHEMBL1718496 | 0.82 | RXFP1 (0.75) | RXFP1POLBMAPTALDH1A1HSD17B10 | |
| SCHEMBL3704786 | 0.79 | RXFP1 (0.67) | RXFP1POLBMAPTAPOBEC3ACTDSP1 | |
| SCHEMBL5658010 | 0.78 | RXFP1 (0.59) | RXFP1POLBMAPTAPOBEC3ACTDSP1 | |
| SCHEMBL1719266 | 0.77 | MAPT (0.78) | RXFP1POLBMAPTALDH1A1HSD17B10 | |
| SCHEMBL3060904 | 0.77 | RXFP1 (0.67) | RXFP1POLBMAPTAPOBEC3ACTDSP1 | |
| SCHEMBL1718356 | 0.77 | ALDH1A1 (0.74) | RXFP1POLBMAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506196-B1 | PYRAZOLOPYRIMIDINES AS SODIUM CHANNEL INHIBITORS | ICAGEN INC (US) | 2012-01-18 | — | — | EP | claimed |