Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | MMP12 | P39900 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12419024 | 0.83 | CA12 (0.55) | CA12CA1CA2CA4CA7 | |
| SCHEMBL21100152 | 0.79 | IAPP (0.46) | IAPPGABRA1GABRB2HSD11B1SMN1; SMN2 | |
| SCHEMBL10585673 | 0.79 | CA12 (0.50) | CA12CA1CA2CA4CA7 | |
| SCHEMBL11274785 | 0.77 | CA12 (0.45) | CA12CA1CA2CA4CA7 | |
| SCHEMBL26564933 | 0.76 | L3MBTL1 (0.47) | IAPPGABRA1GABRB2HSD11B1LMNA | |
| SCHEMBL29210932 | 0.75 | GABRA1 (0.44) | IAPPGABRA1GABRB2HSD11B1PTGS2 | |
| SCHEMBL3110101 | 0.72 | CA12 (0.51) | CA12CA1CA2CA4CA7 | |
| SCHEMBL156141 | 0.72 | AKR1B1 (0.63) | CA12CA2IAPPGABRA1GABRB2 | |
| SCHEMBL30610413 | 0.72 | AKR1B1 (0.63) | CA12CA2IAPPGABRA1GABRB2 | |
| SCHEMBL363774 | 0.72 | CTBP2 (0.53) | HPGDPTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1998741-B1 | SKIN LIGHTENING AGENTS, COMPOSITIONS AND METHODS | UNILEVER PLC (GB) | 2012-03-07 | — | — | EP | disclosed |