Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | IAPP | P10997 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21100152 | 0.91 | IAPP (0.46) | L3MBTL1IAPPHSD11B1AKR1B1GABRA1 | |
| SCHEMBL29210932 | 0.87 | GABRA1 (0.44) | IAPPHSD11B1AKR1B1GABRA1GABRB2 | |
| SCHEMBL6805430 | 0.87 | L3MBTL1 (0.57) | L3MBTL1IAPPAKR1B1CYP3A4GABRA1 | |
| SCHEMBL7150622 | 0.85 | L3MBTL1 (0.52) | L3MBTL1IAPPAKR1B1CYP3A4GABRA1 | |
| Benzene SCHEMBL10992898 | 0.84 | L3MBTL1 (0.60) | L3MBTL1IAPPAKR1B1CYP3A4ALDH1A1 | |
| SCHEMBL30610413 | 0.79 | AKR1B1 (0.63) | IAPPAKR1B1GABRA1GABRB2 | |
| SCHEMBL363774 | 0.79 | CTBP2 (0.53) | ALDH1A1MAPTGAASMN1; SMN2NPC1 | |
| SCHEMBL156141 | 0.79 | AKR1B1 (0.63) | IAPPAKR1B1GABRA1GABRB2 | |
| SCHEMBL8915286 | 0.79 | SLC6A2 (0.41) | IAPPHSD11B1ALDH1A1LMNA | |
| SCHEMBL8083911 | 0.79 | GABRA1 (0.47) | IAPPHSD11B1AKR1B1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | Atea Pharmaceuticals, Inc. (US) | 2023-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230331751-A1 | STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES | NUDT1, PNP, ATIC | L3MBTL1 3712/4885IAPP 2154/4885HSD11B1 2381/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.