SCHEMBL17197837

SCHEMBL17197837

C/C=C/C=C/C(=O)OC(O)CO

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
HTT P42858 1/20 0.34
CNR2 P34972 4/20 0.33
CNR1 P21554 2/20 0.33
PPARG P37231 1/20 0.33
PPARD Q03181 1/20 0.33
PPARA Q07869 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19471888 1.00 LMNA (0.34) LMNAMAPK1HTTCNR2CNR1
SCHEMBL28954263 0.85 LMNA (0.33) LMNAMAPK1HTTCNR2CNR1
SCHEMBL9160314 0.85 TSHR (0.34) LMNAMAPK1HTTCNR2CNR1
SCHEMBL9160338 0.85 TSHR (0.34) LMNAMAPK1HTTCNR2CNR1
SCHEMBL5740275 0.82 MAPK1 (0.35) LMNAMAPK1HTTCNR2CNR1
SCHEMBL9398163 0.81 ACHE (0.34) LMNAMAPK1HTTCNR2CNR1
SCHEMBL9398153 0.81 ACHE (0.34) LMNAMAPK1HTTCNR2CNR1
SCHEMBL10945779 0.81 LMNA (0.38) LMNAMAPK1HTTCNR2CNR1
SCHEMBL9396127 0.81 CNR2 (0.37) LMNAMAPK1HTTCNR2CNR1
SCHEMBL9396123 0.81 CNR2 (0.37) LMNAMAPK1HTTCNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2957591-B1 REMEDIATION OF YELLOWING IN A COATING FORMULATION CONTAINING A SORBATE ESTER OR A SORBAMIDE COALESCENT ROHM & HAAS (US) 2018-07-11 EP disclosed
US-9828510-B2 Sorbic acid ester containing coatings composition ROHM AND HAAS COMPANY (US) 2017-11-28 US disclosed
US-9828510-B2 Sorbic acid ester containing coatings composition ROHM AND HAAS COMPANY (US) 2017-11-28 US disclosed
US-20170305831-A1 PREPARATION OF A SORBATE ESTER DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-26 US disclosed
US-9714359-B2 Remediation of yellowing in a coatings formulation containing a sorbate ester or a sorbamide coalescent ROHM AND HAAS COMPANY (US) 2017-07-25 US disclosed
US-9714359-B2 Remediation of yellowing in a coatings formulation containing a sorbate ester or a sorbamide coalescent ROHM AND HAAS COMPANY (US) 2017-07-25 US disclosed
US-20170037266-A1 SORBATE ESTER OR SORBAMIDE COALESCENT IN A COATINGS FORMULATION THE DOW CHEMICAL COMPANY (US) 2017-02-09 US disclosed
US-20170037266-A1 SORBATE ESTER OR SORBAMIDE COALESCENT IN A COATINGS FORMULATION THE DOW CHEMICAL COMPANY (US) 2017-02-09 US disclosed
US-20160272825-A1 SORBIC ACID ESTER CONTAINING COATINGS COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2016-09-22 US disclosed
US-20160272825-A1 SORBIC ACID ESTER CONTAINING COATINGS COMPOSITION DOW GLOBAL TECHNOLOGIES LLC (US) 2016-09-22 US disclosed
EP-3070129-A1 SORBIC ACID ESTER CONTAINING COATINGS COMPOSITION Dow Global Technologies LLC (US) 2016-09-21 EP disclosed
EP-3029116-A1 SORBIC ACID ESTER COMPOSITION Dow Global Technologies LLC (US) 2016-06-08 EP disclosed
US-20160152856-A1 SORBIC ACID ESTER COMPOSITION ROHM & HAAS (US) 2016-06-02 US disclosed
US-20160152856-A1 SORBIC ACID ESTER COMPOSITION ROHM & HAAS (US) 2016-06-02 US disclosed
EP-2957591-A1 REMEDIATION OF YELLOWING IN A COATING FORMULATION CONTAINING A SORBATE ESTER OR A SORBAMIDE COALESCENT Rohm and Haas Company (US) 2015-12-23 EP disclosed
US-20150361290-A1 REMEDIATION OF YELLOWING IN A COATINGS FORMULATION CONTAINING A SORBATE ESTER OR A SORBAMIDE COALESCENT ROHM AND HAAS COMPANY 2015-12-17 US disclosed
US-20150361290-A1 REMEDIATION OF YELLOWING IN A COATINGS FORMULATION CONTAINING A SORBATE ESTER OR A SORBAMIDE COALESCENT ROHM AND HAAS COMPANY 2015-12-17 US disclosed
WO-2015157929-A1 SORBATE ESTER OR SORBAMIDE COALESCENT IN COATINGS FORMULATION DOW GLOBAL TECHNOLOGIES LLC (US) 2015-10-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170305831-A1 PREPARATION OF A SORBATE ESTER HAO2, SORBS1, HAO1 LMNA 2010/4885MAPK1 1854/4885HTT 274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.