Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 8/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720491 | 0.84 | MEN1 (0.57) | HTR6TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL27495237 | 0.83 | IDO1 (0.55) | MAP3K14IDO1HTR6TUBB4ATUBB | |
| SCHEMBL1720216 | 0.81 | CYP1A2 (0.55) | HTR6TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1719473 | 0.70 | AHR (0.46) | MAPTMEN1KMT2ALMNA | |
| SCHEMBL9269177 | 0.70 | MAP2 (0.62) | HTR6HTR7MAPTHTR1BHTR2A | |
| SCHEMBL31105623 | 0.69 | MAP3K14 (0.76) | MAP3K14HTR6HTR7MAPTHTR1B | |
| SCHEMBL1757734 | 0.69 | LMNA (0.69) | MAP3K14HTR6HTR7MAPTHTR1B | |
| SCHEMBL9843379 | 0.68 | LMNA (0.56) | MAP3K14IDO1HTR6TUBB4ATUBB | |
| SCHEMBL30547019 | 0.68 | LMNA (0.56) | MAP3K14IDO1HTR6TUBB4ATUBB | |
| SCHEMBL30661856 | 0.68 | HTR6 (0.53) | MAP3K14HTR6HTR7MAPTHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1334968-B1 | PROCESS FOR PRODUCING SUBSTITUTED ANILINE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2012-01-11 | — | — | EP | disclosed |
| US-7820861-B2 | chemical intermediate for a sulfonanilide of 4,6-dimethoxypyrmidine derivative herbicide | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-26 | — | — | US | disclosed |
| EP-2025665-B1 | Process for producing substituted aniline compound | IHARA CHEMICAL IND CO (JP) | 2010-09-15 | — | — | EP | disclosed |
| US-7531654-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-7521555-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| US-7504503-B2 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2009-03-17 | — | — | US | disclosed |
| EP-2025665-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) | 2009-02-18 | — | — | EP | disclosed |
| US-7271263-B2 | Process for production of substituted aniline compound | IHARA CHEMICAL INDUSTRY, CO., LTD. (JP) | 2007-09-18 | — | — | US | disclosed |
| US-20070213561-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070213532-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20070213533-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-09-13 | — | — | US | disclosed |
| US-20060281765-A1 | Process for producing substituted aniline compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2006-12-14 | — | — | US | disclosed |
| US-20040034251-A1 | Process for production of substituted aniline compound | 1HARA CHEMICAL INDUSTRY CO., LT.D. (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-1334968-A1 | PROCESS FOR PRODUCING SUBSTITUTED ANILINE COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2003-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034251-A1 | Process for production of substituted aniline compound | NAT1, CBR3, AADAC | MAP3K14 3711/4885IDO1 34/4885HTR6 741/4885 |
| US-20070213561-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | MAP3K14 3260/4885IDO1 64/4885HTR6 783/4885 |
| US-20060281765-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | MAP3K14 3260/4885IDO1 64/4885HTR6 783/4885 |
| US-20070213532-A1 | Process for producing substituted aniline compound | CBR3, AADAC, NAT1 | MAP3K14 3260/4885IDO1 64/4885HTR6 783/4885 |
| US-20070213533-A1 | Process for producing substituted aniline compound | AADAC, NAT1, CBR3 | MAP3K14 3166/4885IDO1 74/4885HTR6 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.