Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | PDE5A | O76074 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3621787 | 0.89 | ALDH1A1 (0.67) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL17028033 | 0.85 | PTGER4 (0.54) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL30495303 | 0.85 | PTGER4 (0.54) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL18937640 | 0.84 | PDE5A (0.45) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL3082745 | 0.81 | F2RL3 (0.61) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4478716 | 0.81 | F2RL3 (0.60) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL13618343 | 0.79 | F2RL3 (0.66) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4028940 | 0.79 | ESR1 (0.69) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL17322904 | 0.79 | HSD17B10 (0.55) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL28982383 | 0.79 | ALDH1A1 (0.71) | F2RL3ALDH1A1HSD17B10CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9573946-B2 | Compounds and methods for inhibiting fascin | NOVITA PHARMACEUTICALS, INC. (US) | 2017-02-21 | — | — | US | disclosed |
| US-20150299191-A1 | COMPOUNDS AND METHODS FOR INHIBITING FASCIN | CORNELL UNIVERSITY | 2015-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150299191-A1 | COMPOUNDS AND METHODS FOR INHIBITING FASCIN | FSCN1, MTPN, MYOF | F2RL3 1365/4885ALDH1A1 3976/4885HSD17B10 1336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.