SCHEMBL17199708

SCHEMBL17199708

Brc1ccc2c(c1)C(=Cc1ccc(C=C3c4cc(Br)ccc4-c4ccc(Br)cc43)cc1)c1cc(Br)ccc1-2

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.48
LCK P06239 1/20 0.46
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
PTPRC P08575 1/20 0.42
PLK4 O00444 1/20 0.41
APP P05067 2/20 0.40
MAOA P21397 1/20 0.39
MAOB P27338 1/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
CYP19A1 P11511 3/20 0.39
CYP11B2 P19099 3/20 0.39
CYP11B1 P15538 2/20 0.39
ERBB2 P04626 1/20 0.38
BCL2 P10415 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17199713 0.91 LCK (0.50) S100A4LCKKMT2AMEN1PTPRC
SCHEMBL1242518 0.90 PTPRC (0.47) S100A4LCKKMT2AMEN1PTPRC
SCHEMBL17199705 0.89 LCK (0.40) S100A4LCKKMT2AMEN1PTPRC
SCHEMBL9177130 0.86 CYP19A1 (0.48) S100A4LCKKMT2AMEN1PTPRC
SCHEMBL9177137 0.86 CYP19A1 (0.48) S100A4LCKKMT2AMEN1PTPRC
SCHEMBL14421802 0.86 APP (0.51) LCKAPPMAOB
SCHEMBL3814228 0.86 APP (0.51) KMT2AMEN1APPMAOAMAOB
SCHEMBL17199715 0.85 S100A4 (0.43) S100A4LCKPTPRCPLK4APP
SCHEMBL17199706 0.83 PTPRC (0.39) S100A4LCKKMT2AMEN1PTPRC
SCHEMBL17209529 0.83 LCK (0.36) S100A4LCKKMT2AMEN1PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed