SCHEMBL17199713

SCHEMBL17199713

Brc1ccc2c(c1)C(=Cc1cc(C=C3c4cc(Br)ccc4-c4ccc(Br)cc43)cc(C=C3c4cc(Br)ccc4-c4ccc(Br)cc43)c1)c1cc(Br)ccc1-2

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LCK P06239 2/20 0.50
S100A4 P26447 1/20 0.48
PTPRC P08575 1/20 0.42
MAP1LC3B Q9GZQ8 1/20 0.39
PLK4 O00444 2/20 0.37
BCL2 P10415 2/20 0.37
MCL1 Q07820 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CYP19A1 P11511 2/20 0.35
CYP11B1 P15538 2/20 0.35
CYP11B2 P19099 2/20 0.35
NPSR1 Q6W5P4 1/20 0.34
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17199708 0.91 S100A4 (0.48) LCKS100A4PTPRCPLK4BCL2
SCHEMBL17199715 0.90 S100A4 (0.43) LCKS100A4PTPRCPLK4CYP19A1
SCHEMBL1242518 0.85 PTPRC (0.47) LCKS100A4PTPRCMEN1KMT2A
SCHEMBL9177130 0.82 CYP19A1 (0.48) LCKS100A4PTPRCMEN1KMT2A
SCHEMBL9177137 0.82 CYP19A1 (0.48) LCKS100A4PTPRCMEN1KMT2A
SCHEMBL1242570 0.82 LCK (0.41) LCKS100A4PTPRCMAP1LC3BPLK4
SCHEMBL17199705 0.81 LCK (0.40) LCKS100A4PTPRCPLK4MEN1
SCHEMBL17199700 0.78 PTPRC (0.48) LCKS100A4PTPRCBCL2MCL1
SCHEMBL14421802 0.78 APP (0.51) LCKAPP
SCHEMBL3814228 0.78 APP (0.51) MEN1KMT2ANPSR1APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed