SCHEMBL17199715

SCHEMBL17199715

Brc1ccc2c(c1)C(=Cc1cccc(C=C3c4cc(Br)ccc4-c4ccc(Br)cc43)c1)c1cc(Br)ccc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.43
LCK P06239 1/20 0.42
PTPRC P08575 1/20 0.42
ALDH1A1 P00352 1/20 0.41
HSD11B1 P28845 1/20 0.41
MAOA P21397 3/20 0.40
MAOB P27338 3/20 0.40
NPSR1 Q6W5P4 1/20 0.39
TUBB4A P04350 1/20 0.39
TUBB P07437 1/20 0.39
TUBA3C P0DPH7 1/20 0.39
AR P10275 1/20 0.39
TUBA1B P68363 1/20 0.39
TUBA4A P68366 1/20 0.39
TUBB4B P68371 1/20 0.39
TUBB3 Q13509 1/20 0.39
TUBB2A Q13885 1/20 0.39
TUBB8 Q3ZCM7 1/20 0.39
TUBA3E Q6PEY2 1/20 0.39
TUBA1A Q71U36 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17199713 0.90 LCK (0.50) S100A4LCKPTPRCNPSR1PLK4
SCHEMBL1242518 0.88 PTPRC (0.47) S100A4LCKPTPRCALDH1A1CYP1A2
SCHEMBL17199708 0.85 S100A4 (0.48) S100A4LCKPTPRCMAOAMAOB
SCHEMBL9177130 0.85 CYP19A1 (0.48) S100A4LCKPTPRCTUBB4ATUBB
SCHEMBL9177137 0.85 CYP19A1 (0.48) S100A4LCKPTPRCTUBB4ATUBB
SCHEMBL28640571 0.80 ALDH1A1 (0.50) ALDH1A1HSD11B1MAOAMAOBNPSR1
SCHEMBL19420890 0.80 APP (0.45) S100A4LCKPTPRCTUBB4ATUBB
SCHEMBL17199700 0.78 PTPRC (0.48) S100A4LCKPTPRCCYP1A2MAPK1
SCHEMBL17199705 0.76 LCK (0.40) S100A4LCKPTPRCALDH1A1MAOA
SCHEMBL14506934 0.74 AMY1A (0.42) S100A4LCKPTPRCALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015161989-A1 HOLE-TRANSPORT MATERIALS FOR ORGANIC SOLAR CELLS OR ORGANIC OPTICAL SENSORS BASF SE (DE) 2015-10-29 WO disclosed
EP-2937399-A1 Hole-transport materials for organic solar cells or organic optical sensors BASF SE (DE) 2015-10-28 EP disclosed