SCHEMBL17199746

SCHEMBL17199746

C#C[Si](C)(O[Si](C)(C#C)c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17199733 0.90 ESR1 (0.32) ESR1ESR2
SCHEMBL28268841 0.79 ESR1 (0.31) ESR1ESR2
SCHEMBL935728 0.73 ESR1 (0.39) ESR1ESR2
SCHEMBL9732848 0.73 ESR1 (0.39) ESR1ESR2
SCHEMBL587376 0.73 ESR1 (0.39) ESR1ESR2
SCHEMBL9444693 0.73 ESR1 (0.39) ESR1ESR2
SCHEMBL6256337 0.72 NR1H2 (0.37) ESR1ESR2
SCHEMBL17199740 0.71
SCHEMBL10838037 0.69 ESR1 (0.44) ESR1ESR2
SCHEMBL8520332 0.68 ESR1 (0.35) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2937375-B1 NOVEL ETHYNYL-GROUP-CONTAINING ORGANOPOLYSILOXANE COMPOUND, METHOD FOR PRODUCING STRAIGHT-CHAIN ORGANOPOLYSILOXANE COMPOUND CONTAINING ETHYNYL GROUP AT BOTH MOLECULAR CHAIN ENDS, METHOD FOR PRODUCING ALKOXYSILYL-ETHYNYL-GROUP-TERMINATED ORGANOSILOXANE POLYMER, ROOM-TEMPERATURE-CURABLE COMPOSITION, AND MOLDED ARTICLE THAT IS CURED PRODUCT OF SAME SHINETSU CHEMICAL CO (JP) 2020-08-05 EP disclosed
CN-104870524-B The manufacture method of alkoxysilane group ethylidene end organic siloxane polymer, room-temperature-curable composition and its solidfied material 信越化学工业株式会社 2017-07-11 CN disclosed
US-9475969-B2 Organopolysiloxane compound having ethynyl groups, method for preparing linear organopolysiloxane compound having ethynyl groups at both terminals of molecular chain, method for preparing organopolysiloxane polymer having alkoxysilyl-ethylene group at terminal, room temperature curable composition and molded product which is cured product thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-10-25 US disclosed
US-20150315428-A1 NOVEL ORGANOPOLYSILOXANE COMPOUND HAVING ETHYNYL GROUPS, METHOD FOR PREPARING LINEAR ORGANOPOLYSILOXANE COMPOUND HAVING ETHYNYL GROUPS AT BOTH TERMINALS OF MOLECULAR CHAIN, METHOD FOR PREPARING ORGANOSILOXANE POLYMER HAVING ALKOXYSILYL-ETHYLENE GROUP AT TERMINAL, ROOM TEMPERATURE CURABLE COMPOSITION AND MOLDED PRODUCT WHICH IS CURED PRODUCT THEREOF SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-11-05 US disclosed
EP-2937375-A1 NOVEL ETHYNYL-GROUP-CONTAINING ORGANOPOLYSILOXANE COMPOUND, METHOD FOR PRODUCING STRAIGHT-CHAIN ORGANOPOLYSILOXANE COMPOUND CONTAINING ETHYNYL GROUP AT BOTH MOLECULAR CHAIN ENDS, METHOD FOR PRODUCING ALKOXYSILYL-ETHYNYL-GROUP-TERMINATED ORGANOSILOXANE POLYMER, ROOM-TEMPERATURE-CURABLE COMPOSITION, AND MOLDED ARTICLE THAT IS CURED PRODUCT OF SAME Shin-Etsu Chemical Co., Ltd. (JP) 2015-10-28 EP disclosed