Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788362 | 0.79 | ACHE (0.35) | — | |
| SCHEMBL7403172 | 0.77 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL8521137 | 0.76 | — | — | |
| SCHEMBL9732848 | 0.73 | ESR1 (0.39) | ESR1ESR2KCNH3 | |
| SCHEMBL6628841 | 0.72 | MAPK1 (0.31) | — | |
| SCHEMBL8785246 | 0.72 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL121414 | 0.72 | ESR1 (0.42) | ESR1ESR2 | |
| SCHEMBL179863 | 0.71 | ESR1 (0.35) | ESR1ESR2 | |
| SCHEMBL48955 | 0.70 | ESR1 (0.41) | ESR1ESR2 | |
| SCHEMBL9444693 | 0.69 | ESR1 (0.39) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0742223-B1 | A method of preparing a derivative of optically active azetidin-2-one | TAKASAGO PERFUMERY CO LTD (JP) | 1999-11-17 | — | — | EP | claimed |