SCHEMBL935728

SCHEMBL935728

C#C[Si](C)(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
TSHR P16473 3/20 0.36
ACHE P22303 2/20 0.36
LMNA P02545 2/20 0.36
ALOX12 P18054 1/20 0.36
NR1H2 P55055 2/20 0.32
NR1H3 Q13133 2/20 0.32
MAPT P10636 1/20 0.31
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
NPC1 O15118 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
NFKB1 P19838 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9444693 0.79 ESR1 (0.39) ESR1ESR2TSHRACHELMNA
SCHEMBL9732848 0.79 ESR1 (0.39) ESR1ESR2TSHRACHELMNA
SCHEMBL587376 0.79 ESR1 (0.39) ESR1ESR2TSHRACHELMNA
SCHEMBL10725856 0.78 ESR1 (0.42) ESR1ESR2TSHRACHELMNA
SCHEMBL17199746 0.73 ESR1 (0.35) ESR1ESR2
SCHEMBL936542 0.72 ESR1 (0.32) ESR1ESR2
SCHEMBL9444685 0.72 ESR1 (0.32) ESR1ESR2TSHRCYP3A4
SCHEMBL10708107 0.72 ESR1 (0.32) ESR1ESR2
SCHEMBL12191034 0.72 ESR1 (0.38) ESR1ESR2TSHRACHELMNA
Biphenyl SCHEMBL27849622 0.70 ALDH1A1 (0.50) MAPTNPC1NFKB1RAB9ANFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 104 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3643706-B1 MODIFIED NUCLEIC ACID MONOMERS AND OLIGONUCLEIC ACID ANALOGUES, WITH HIGH BIOLOGICAL STABILITY AND TARGET GENE SILENCING ACTIVITY, FOR USE IN THERAPY AND DIAGNOSIS OF CANCER AND VIRAL DISEASES EISAI R&D MAN CO LTD (JP) 2023-11-15 EP claimed
US-11814462-B2 Functionalized cyclic polymers and methods of preparing same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-14 US claimed
US-20220056167-A1 Functionalized Cyclic Polymers and Methods of Preparing Same NATIONAL SCIENCE FOUNDATION 2022-02-24 US claimed
WO-2020223672-A1 FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) 2020-11-05 WO claimed
CN-111211355-A High-voltage lithium ion battery electrolyte additive, electrolyte and battery thereof 松山湖材料实验室 2020-05-29 CN claimed
EP-2921499-B1 METHOD FOR LIQUID-PHASE SYNTHESIS OF NUCLEIC ACIDS TAKEDA PHARMACEUTICALS CO (JP) 2020-01-22 EP claimed
EP-2834253-B1 THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES CENTRE NAT DE LA RECH SCIENT (C N R S ) (FR) 2017-03-29 EP claimed
EP-2834253-A1 THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES Centre National de la Recherche Scientifique (CNRS) (FR) 2015-02-11 EP claimed
WO-2013150106-A1 THIOL COMPOUNDS AND THE USE THEREOF FOR THE SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2013-10-10 WO claimed
CN-101260175-A Silicon-containing copolymer with phenylacetylene end group UNIV EAST CHINA SCIENCE & TECH (CN) 2008-09-10 CN claimed
CN-100400571-C High-temperature-resistance silicon-containing copolymer and its preparing method UNIV EAST CHINA SCIENCE & TECH (CN) 2008-07-09 CN claimed
EP-0948514-B1 METHOD FOR THE SYNTHESIS OF NUCLEOTIDE OR OLIGONUCLEOTIDE PHOSPHORAMIDITES ISIS PHARMACEUTICALS INC (US) 2005-04-27 EP claimed
EP-0948512-B1 METHOD OF SYNTHESIZING PHOSPHOROTHIOATE OLIGONUCLEOTIDES ISIS PHARMACEUTICALS INC (US) 2004-10-06 EP claimed
CN-120048605-A High-Wen-resistant iron-boron magnetic material and preparation method thereof 东莞市东正磁业有限公司 2025-05-27 CN disclosed
CN-118994924-A Plastic plate for cutting silicon wafer and preparation method and application thereof 广东金湾高景太阳能科技有限公司 2024-11-22 CN disclosed
CN-118325466-A Anti-icing and deicing coating with excellent durability and preparation method thereof 重庆大学 2024-07-12 CN disclosed
US-20070249802-A1 ACENE-THIOPHENE COPOLYMERS WITH SILETHYNLY GROUPS 3M INNOVATIVE PROPERTIES COMPANY 2007-10-25 US disclosed
US-20070249087-A1 ELECTRONIC DEVICES CONTAINING ACENE-THIOPHENE COPOLYMERS WITH SILYLETHYNYL GROUPS 3M INNOVATIVE PROPERTIES COMPANY 2007-10-25 US disclosed
CN-1763053-A Diphenylacetylene silane novle synthesis method UNIV EAST CHINA SCIENCE & TECH (CN) 2006-04-26 CN disclosed
US-4714481-A Gas separation membrane MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-12-22 US disclosed