SCHEMBL17199822

SCHEMBL17199822

CC(C)Oc1cccc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.50

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
FGFR1 P11362 1/20 0.46
PPARG P37231 2/20 0.44
PTPN1 P18031 1/20 0.42
CCKBR P32239 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12977149 0.86 KDM4E (0.55) KDM4EATML3MBTL1FGFR1PTPN1
SCHEMBL10299341 0.83 PIM1 (0.46) KDM4EFGFR1
SCHEMBL10047610 0.83 PTPN1 (0.54) KDM4EATML3MBTL1FGFR1PTPN1
SCHEMBL14454763 0.81 KDM4E (0.55) KDM4EATML3MBTL1FGFR1
SCHEMBL16890333 0.79 KDM4E (0.57) KDM4EATML3MBTL1FGFR1PPARG
SCHEMBL19003188 0.78 KDM4E (0.44) KDM4EATML3MBTL1FGFR1PTPN1
SCHEMBL57391 0.78 L3MBTL1 (0.73) KDM4EATML3MBTL1
SCHEMBL29351958 0.78 L3MBTL1 (0.73) KDM4EATML3MBTL1
SCHEMBL29371952 0.78 L3MBTL1 (0.73) KDM4EATML3MBTL1
SCHEMBL28477376 0.77 KDM4E (0.61) KDM4EATML3MBTL1FGFR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2937355-B1 PHOSPHORUS COMPOUND AND TRANSITION METAL COMPLEX OF THE SAME TAKASAGO PERFUMERY CO LTD (JP) 2017-06-28 EP disclosed
US-9416148-B2 Phosphorus compound and transition metal complex of the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-08-16 US disclosed
US-9416148-B2 Phosphorus compound and transition metal complex of the same TAKASAGO INTERNATIONAL CORPORATION (JP) 2016-08-16 US disclosed
US-20150307531-A1 PHOSPHORUS COMPOUND AND TRANSITION METAL COMPLEX OF THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-10-29 US disclosed
US-20150307531-A1 PHOSPHORUS COMPOUND AND TRANSITION METAL COMPLEX OF THE SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-10-29 US disclosed
EP-2937355-A1 PHOSPHORUS COMPOUND AND TRANSITION METAL COMPLEX OF THE SAME Takasago International Corporation (JP) 2015-10-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150307531-A1 PHOSPHORUS COMPOUND AND TRANSITION METAL COMPLEX OF THE SAME P2RY10, PTH1R, INPP5A KDM4E 3631/4885ATM 2549/4885L3MBTL1 3743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.