Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 8/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | STAT1 | P42224 | 2/20 | 0.43 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29011015 | 0.85 | S1PR3 (0.43) | S1PR3S1PR1RAB9ANPC1STAT1 | |
| SCHEMBL841342 | 0.74 | S1PR3 (0.57) | S1PR3S1PR1RAB9ANPC1STAT1 | |
| SCHEMBL28856869 | 0.72 | S1PR3 (0.58) | S1PR3S1PR1RAB9ANPC1STAT1 | |
| SCHEMBL875579 | 0.71 | TMPRSS15 (0.49) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL18606260 | 0.70 | SLC6A3 (0.48) | S1PR3S1PR1RAB9ANPC1STAT1 | |
| SCHEMBL3062466 | 0.69 | RAB9A (0.56) | S1PR3S1PR1RAB9ANPC1STAT1 | |
| SCHEMBL13835610 | 0.69 | RAB9A (0.56) | S1PR3S1PR1RAB9ANPC1STAT1 | |
| SCHEMBL20305303 | 0.69 | SMN1; SMN2 (0.65) | S1PR3S1PR1RAB9ANPC1STAT1 | |
| SCHEMBL22554186 | 0.68 | S1PR3 (0.62) | S1PR3S1PR1RAB9ANPC1STAT1 | |
| SCHEMBL892137 | 0.68 | S1PR3 (0.62) | S1PR3S1PR1RAB9ANPC1STAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635567-B1 | INDOLE DERIVATIVES | RICHTER GEDEON NYRT (HU) | 2015-10-28 | — | — | EP | claimed |