SCHEMBL1720006

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6987084	0.81	LMNA (0.50)	LMNAHPGDFFAR1MAPK1TSHR
	SCHEMBL1719815	0.80	ALDH1A1 (0.39)	LMNAHPGDMAPK1TSHRALDH1A1
	SCHEMBL1720086	0.78	SMN1; SMN2 (0.40)	LMNAHPGDMAPK1TSHRALDH1A1
	SCHEMBL24700466	0.78	LMNA (0.66)	LMNAHPGDFFAR1MAPK1TSHR
	SCHEMBL1719852	0.77	TSHR (0.35)	HPGDTSHRALDH1A1MAPTSMN1; SMN2
	SCHEMBL1719384	0.77	KMT2A (0.35)	ALDH1A1SMN1; SMN2MEN1KMT2ANPC1
	SCHEMBL1719387	0.76	ALDH1A1 (0.40)	LMNAHPGDMAPK1TSHRALDH1A1
	SCHEMBL3263155	0.76	LMNA (0.72)	LMNAHPGDFFAR1MAPK1TSHR
	SCHEMBL1719442	0.76	MAPT (0.30)	MAPTKMT2A
	SCHEMBL1719407	0.75	ALDH1A1 (0.45)	LMNAHPGDMAPK1TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.