SCHEMBL17200149

SCHEMBL17200149

Cn1c(N)nc2nc[nH]c2c1=O.O=C1CCNC(=O)N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.41
ATAD2 Q6PL18 1/20 0.39
ADORA2A P29274 6/20 0.38
PDE4A P27815 6/20 0.38
PDE4B Q07343 6/20 0.38
PDE4C Q08493 6/20 0.38
PDE4D Q08499 6/20 0.38
ADORA2B P29275 5/20 0.38
ADORA1 P30542 2/20 0.38
PIK3CD O00329 1/20 0.38
ALPL P05186 1/20 0.38
ADORA3 P0DMS8 1/20 0.38
TMIGD3 P0DMS9 1/20 0.38
CYP2C19 P33261 1/20 0.38
HIF1A Q16665 1/20 0.38
CYP1A2 P05177 2/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38
PNP P00491 1/20 0.36
MAPK1 P28482 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20867 0.83 ATAD2 (0.53) ATAD2ADORA2APDE4APDE4BPDE4C
SCHEMBL27602647 0.82 ATAD2 (0.49) ATAD2ADORA2APDE4APDE4BPDE4C
Hydrochloric Acid SCHEMBL27339406 0.82 ATAD2 (0.51) ATAD2ADORA2APDE4APDE4BPDE4C
Water SCHEMBL27738785 0.82 ADORA2A (0.54) ATAD2ADORA2APDE4APDE4BPDE4C
SCHEMBL17200148 0.81 CRBN (0.41) CRBNATAD2ADORA2APDE4APDE4B
2,6-Diaminopurine SCHEMBL22775220 0.78 PDPK1 (0.60) CRBNADORA2AADORA1PNPHRH4
Thiophene SCHEMBL27638390 0.75 ATAD2 (0.44) ATAD2ADORA2APDE4APDE4BPDE4C
Hydrochlorthiazide SCHEMBL27456436 0.73 ATAD2 (0.40) ATAD2ADORA2APDE4APDE4BPDE4C
Oxazole SCHEMBL27309879 0.73 ATAD2 (0.40) ATAD2ADORA2APDE4APDE4BPDE4C
SCHEMBL27310857 0.69 MGMT (0.41) ATAD2ADORA2APDE4APDE4BPDE4C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2995895-A1 METHODS AND COMPONENTS FOR THERMAL ENERGY STORAGE Caloritum NV (BE) 2016-03-16 EP disclosed
EP-2668459-B1 METHODS AND COMPONENTS FOR THERMAL ENERGY STORAGE CALORITUM NV (BE) 2015-10-28 EP disclosed