Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 10/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.48 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.48 |
| ▸ | LSS | P48449 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | APAF1 | O14727 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28647303 | 1.00 | DNM1 (0.56) | DNM1HTTSLC22A1HSP90AA1RAD52 | |
| SCHEMBL27266023 | 0.97 | DNM1 (0.55) | DNM1HTTSLC22A1LSSKMT2A | |
| SCHEMBL10440002 | 0.97 | DNM1 (0.55) | DNM1HTTSLC22A1LSSKMT2A | |
| Iodide SCHEMBL3097826 | 0.95 | DNM1 (0.56) | DNM1HTTSLC22A1HSP90AA1RAD52 | |
| SCHEMBL19193343 | 0.95 | DNM1 (0.50) | DNM1HTTSLC22A1HSP90AA1RAD52 | |
| SCHEMBL5944573 | 0.87 | BBOX1 (0.48) | DNM1HTTSLC22A1LSSKMT2A | |
| SCHEMBL21758278 | 0.87 | BBOX1 (0.52) | DNM1HTTLSSKMT2A | |
| Water SCHEMBL21758279 | 0.84 | BBOX1 (0.50) | DNM1HTTHSP90AA1RAD52LSS | |
| Hydrochloric Acid SCHEMBL2783884 | 0.81 | DNM1 (0.52) | DNM1HTTSLC22A1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL9397468 | 0.81 | DNM1 (0.52) | DNM1HTTSLC22A1HSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150310958-A1 | STRUCTURE CONTAINING METAL MICROPARTICLES | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2015-10-29 | — | — | US | disclosed |
| CN-2444450-Y | Antibiosis leather gloves | HENGYUANXIANG CLOTHING AND DEC (CN) | 2001-08-29 | — | — | CN | disclosed |