Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17037971 | 0.78 | GAA (0.45) | MAOAKDM4EALDH1A1GAAACHE | |
| SCHEMBL17026674 | 0.78 | MAOB (0.53) | MAOAKDM4EALDH1A1GAANPC1 | |
| SCHEMBL17026607 | 0.75 | GAA (0.48) | MAOAKDM4EALDH1A1GAAACHE | |
| SCHEMBL17037979 | 0.73 | NPC1 (0.33) | ALDH1A1NPC1KMT2ARAB9AMEN1 | |
| SCHEMBL17026534 | 0.70 | POLA1 (0.34) | — | |
| SCHEMBL17026637 | 0.68 | MCL1 (0.46) | MAOAKDM4EALDH1A1GAAACHE | |
| SCHEMBL16674816 | 0.63 | MAOA (0.68) | MAOAKDM4EALDH1A1GAAKMT2A | |
| 7-Cyclohexyloxycoumarin SCHEMBL14802688 | 0.62 | MAOA (0.67) | MAOAKDM4EALDH1A1GAAKMT2A | |
| SCHEMBL12075725 | 0.61 | ALDH1A1 (0.66) | MAOAKDM4EALDH1A1GAAACHE | |
| SCHEMBL8806820 | 0.61 | KDM4E (0.61) | KDM4EALDH1A1GAAACHEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10119972-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2018-11-06 | — | — | US | disclosed |
| US-20180011104-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2018-01-11 | — | — | US | disclosed |
| US-9759726-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2017-09-12 | — | — | US | disclosed |
| US-9759726-B2 | Reactive labelling compounds and uses thereof | ACADEMIA SINICA (TW) | 2017-09-12 | — | — | US | disclosed |
| US-20150309041-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-10-29 | — | — | US | disclosed |
| US-20150309041-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | ACADEMIA SINICA (TW) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150309041-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | MPI, AADAC, PAICS | MAOA 135/4885KDM4E 4416/4885ALDH1A1 364/4885 |
| US-20180011104-A1 | REACTIVE LABELLING COMPOUNDS AND USES THEREOF | MPI, AADAC, PAICS | MAOA 135/4885KDM4E 4318/4885ALDH1A1 273/4885 |
| US-10119972-B2 | Reactive labelling compounds and uses thereof | MPI, AADAC, PAICS | MAOA 135/4885KDM4E 4318/4885ALDH1A1 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.