Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 1.00 |
| ▸ | DPYD | Q12882 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | THPO | P40225 | 1/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HBB | P68871 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Thymine SCHEMBL5235 | 1.00 | — | — | |
| Thymine SCHEMBL750450 | 1.00 | ATAD2 (1.00) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL15323914 | 1.00 | ATAD2 (1.00) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL29669526 | 1.00 | — | — | |
| Thymine SCHEMBL2724033 | 0.97 | ATAD2 (0.95) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL8649294 | 0.97 | ATAD2 (0.95) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL5176783 | 0.97 | ATAD2 (0.95) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL935833 | 0.97 | ATAD2 (0.95) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL31403209 | 0.97 | ATAD2 (0.95) | ATAD2DPYDMAPTGAAALDH1A1 | |
| Thymine SCHEMBL4811815 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9522936-B2 | Engineered transcription activator like effector (TALE) proteins | SANGAMO BIOSCIENCES, INC. (US) | 2016-12-20 | — | — | US | disclosed |
| US-20150307561-A1 | ENGINEERED TRANSCRIPTION ACTIVATOR LIKE EFFECTOR (TALE) PROTEINS | SANGAMO BIOSCIENCES, INC. | 2015-10-29 | — | — | US | disclosed |
| WO-2015164748-A1 | ENGINEERED TRANSCRIPTION ACTIVATOR LIKE EFFECTOR (TALE) PROTEINS | SANGAMO BIOSCIENCES, INC. (US) | 2015-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307561-A1 | ENGINEERED TRANSCRIPTION ACTIVATOR LIKE EFFECTOR (TALE) PROTEINS | ZFR, ZFX, TEAD4 | ATAD2 436/4885DPYD 3702/4885MAPT 3455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.