Thymine

Thymine

SCHEMBL8649294

Cc1c[nH]c(=O)[nH]c1=O.[KH]

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATAD2 Q6PL18 1/20 0.95
DPYD Q12882 5/20 0.50
MAPT P10636 3/20 0.50
GAA P10253 3/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.50
CYP19A1 P11511 1/20 0.50
TSHR P16473 1/20 0.50
THPO P40225 1/20 0.50
MTOR P42345 1/20 0.50
HTT P42858 1/20 0.50
HBB P68871 1/20 0.50
PMP22 Q01453 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4C Q9H3R0 1/20 0.39
POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thymine SCHEMBL750450 0.97 ATAD2 (1.00) ATAD2DPYDMAPTGAAALDH1A1
Thymine SCHEMBL15323914 0.97 ATAD2 (1.00) ATAD2DPYDMAPTGAAALDH1A1
Thymine SCHEMBL17201833 0.97 ATAD2 (1.00) ATAD2DPYDMAPTGAAALDH1A1
Thymine SCHEMBL29669526 0.97
Thymine SCHEMBL5235 0.97
Thymine SCHEMBL2724033 0.95 ATAD2 (0.95) ATAD2DPYDMAPTGAAALDH1A1
Thymine SCHEMBL3500839 0.95 ATAD2 (0.95) ATAD2DPYDMAPTGAAALDH1A1
Thymine SCHEMBL5176783 0.95 ATAD2 (0.95) ATAD2DPYDMAPTGAAALDH1A1
Thymine SCHEMBL935833 0.95 ATAD2 (0.95) ATAD2DPYDMAPTGAAALDH1A1
Thymine SCHEMBL31403209 0.95 ATAD2 (0.95) ATAD2DPYDMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0759193-B1 VINYLBENZYL THYMINE MONOMERS AND POLYMERS AND PRODUCTS PREPARED FROM SAME POLAROID CORP (US) 1998-09-09 EP disclosed
US-5708106-A PHOTOCROSSLINKED POLAROID CORPORATION (US) 1998-01-13 US disclosed
US-5616451-A IMAGES BY EXPOSURE TO ACTINIC RADIATION; SOLVENT REMOVAL OF NON-EXPOSED AREAS POLAROID CORPORATION (US) 1997-04-01 US disclosed
EP-0759193-A1 VINYLBENZYL THYMINE MONOMERS AND POLYMERS AND PRODUCTS PREPARED FROM SAME POLAROID CORPORATION (US) 1997-02-26 EP disclosed
WO-1995031755-A1 VINYLBENZYL THYMINE MONOMERS AND POLYMERS AND PRODUCTS PREPARED FROM SAME POLAROID CORPORATION (US) 1995-11-23 WO disclosed
US-5455349-A For polymers useful in photoresists, imaging POLAROID CORPORATION (US) 1995-10-03 US disclosed
US-5395731-A Pendant quaternary ammonium and thymine or uracil groups, diffusion transfer POLAROID CORPORATION (US) 1995-03-07 US disclosed