Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.51 |
| ▸ | ERN1 | O75460 | 2/20 | 0.51 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | RXRB | P28702 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | SELL | P14151 | 1/20 | 0.46 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
| ▸ | SELE | P16581 | 1/20 | 0.46 |
| ▸ | DDT | P30046 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28256321 | 0.90 | KMO (0.55) | KMOERN1RXRARXRBAKR1C3 | |
| SCHEMBL407375 | 0.85 | KMO (0.56) | KMOERN1RXRARXRBGPR35 | |
| SCHEMBL30509760 | 0.84 | KMO (0.51) | KMOERN1RXRARXRBAKR1C3 | |
| SCHEMBL17205336 | 0.84 | KMO (0.51) | KMOERN1RXRARXRBAKR1C3 | |
| SCHEMBL28113286 | 0.79 | FOLH1 (0.56) | KMOERN1RXRARXRBAKR1C3 | |
| SCHEMBL11227165 | 0.78 | KMO (0.72) | KMOERN1RXRARXRBGPR35 | |
| SCHEMBL4171236 | 0.78 | ALOX5 (0.60) | KMOERN1RXRARXRBAKR1C3 | |
| SCHEMBL5567627 | 0.77 | RXRA (0.54) | KMOERN1RXRARXRBAKR1C3 | |
| SCHEMBL16749639 | 0.77 | KMO (0.69) | KMOERN1RXRARXRBAKR1C3 | |
| SCHEMBL29386545 | 0.77 | KMO (0.69) | KMOERN1RXRARXRBAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3134197-A1 | COOPERATIVE CHEMICAL ADSORPTION OF ACID GASES IN FUNCTIONALIZED METAL-ORGANIC FRAMEWORKS | The Regents of The University of California (US) | 2017-03-01 | — | — | EP | disclosed |
| CN-106457120-A | Cooperative chemical adsorption of acid gases in functionalized metal-organic frameworks | 加利福尼亚大学董事会 | 2017-02-22 | — | — | CN | disclosed |
| WO-2015164543-A1 | COOPERATIVE CHEMICAL ADSORPTION OF ACID GASES IN FUNCTIONALIZED METAL-ORGANIC FRAMEWORKS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-10-29 | — | — | WO | disclosed |