Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17205667 | 0.84 | TRPV1 (0.67) | L3MBTL1NPC1RAB9ALMNATRPV1 | |
| SCHEMBL17203188 | 0.80 | TRPV1 (0.73) | TRPV1MEN1KMT2AALDH1A1EPHX2 | |
| SCHEMBL17202845 | 0.79 | TRPV1 (0.76) | TRPV1MEN1KMT2AALDH1A1PKM | |
| SCHEMBL14433758 | 0.78 | L3MBTL1 (0.58) | L3MBTL1NPC1RAB9ALMNAMEN1 | |
| SCHEMBL24575982 | 0.77 | TSHR (0.71) | LMNATRPV1MEN1KMT2APOLB | |
| SCHEMBL1565023 | 0.77 | L3MBTL1 (0.76) | L3MBTL1NPC1RAB9ALMNAMEN1 | |
| Hydrochloric Acid SCHEMBL1815094 | 0.76 | TSHR (0.54) | LMNATRPV1MEN1KMT2AALDH1A1 | |
| SCHEMBL12655254 | 0.76 | TSHR (0.57) | LMNATRPV1MEN1KMT2AALDH1A1 | |
| SCHEMBL17203261 | 0.76 | MAPT (0.51) | NPC1RAB9ALMNATRPV1MEN1 | |
| SCHEMBL12655252 | 0.74 | TSHR (0.51) | LMNATRPV1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | claimed |
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |