Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 9/20 | 0.73 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17203299 | 0.85 | TRPV1 (1.00) | TRPV1TSHRPYGLALDH1A1HPGD | |
| SCHEMBL17203132 | 0.80 | L3MBTL1 (0.55) | TRPV1TSHREPHX2PYGLMEN1 | |
| SCHEMBL17203184 | 0.79 | TRPV1 (0.76) | TRPV1ALDH1A1HPGD | |
| SCHEMBL24575982 | 0.76 | TSHR (0.71) | TRPV1TSHREPHX2MEN1KMT2A | |
| SCHEMBL17202893 | 0.76 | TRPV1 (0.77) | TRPV1MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL12655254 | 0.75 | TSHR (0.57) | TRPV1TSHRPYGLMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1815094 | 0.75 | TSHR (0.54) | TRPV1TSHREPHX2PYGLMEN1 | |
| SCHEMBL12655252 | 0.73 | TSHR (0.51) | TRPV1TSHREPHX2PYGLMEN1 | |
| SCHEMBL12655527 | 0.73 | TSHR (0.55) | TRPV1TSHRPYGLMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1818165 | 0.72 | TSHR (0.50) | TRPV1TSHREPHX2PYGLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | claimed |
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |