Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 9/20 | 0.53 |
| ▸ | DNMT3B | Q9UBC3 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17204628 | 0.88 | DNMT1 (0.60) | DNMT1DNMT3BADRB1FPR2 | |
| SCHEMBL6397616 | 0.86 | DNMT1 (0.46) | DNMT1DNMT3BADRB1FPR2POLB | |
| SCHEMBL231959 | 0.86 | DNMT1 (0.64) | DNMT1DNMT3BADRB1FPR2 | |
| SCHEMBL25837386 | 0.86 | DNMT1 (0.64) | DNMT1DNMT3BADRB1FPR2 | |
| SCHEMBL231960 | 0.86 | DNMT1 (0.64) | DNMT1DNMT3BADRB1FPR2 | |
| SCHEMBL29431942 | 0.86 | DNMT1 (0.64) | DNMT1DNMT3BADRB1FPR2 | |
| SCHEMBL22299584 | 0.86 | DNMT1 (0.64) | DNMT1DNMT3BADRB1FPR2 | |
| SCHEMBL336318 | 0.85 | TYMS (0.55) | DNMT1DNMT3BPOLBTYMS | |
| SCHEMBL1331043 | 0.85 | TYMS (0.55) | DNMT1DNMT3BPOLBTYMS | |
| SCHEMBL23523713 | 0.82 | DNMT1 (0.42) | DNMT1DNMT3BADRB1FPR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162130-A1 | BASE-MODIFIED-NUCLEOSIDE ANALOGS FOR THE DETECTION OF O6-ALKYL GUANINE | ETH ZURICH (CH) | 2015-10-29 | — | — | WO | disclosed |