SCHEMBL336318

SCHEMBL336318

Nc1nc(=O)n([C@H]2CC(O)[C@@H](COP(=O)(O)O)O2)cc1CO

nearest known ligand 0.75

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TYMS P04818 2/20 0.55
POLB P06746 1/20 0.54
DNMT1 P26358 3/20 0.53
DNMT3B Q9UBC3 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1331043 1.00 TYMS (0.55) TYMSPOLBDNMT1DNMT3B
SCHEMBL28011043 0.93 TYMS (0.49) TYMSPOLBDNMT1DNMT3B
SCHEMBL14660974 0.92 POLB (0.55) TYMSPOLBDNMT1DNMT3B
SCHEMBL2926533 0.92 POLB (0.55) TYMSPOLBDNMT1DNMT3B
SCHEMBL16431293 0.92 POLB (0.54) TYMSPOLBDNMT1DNMT3B
SCHEMBL15810651 0.90 POLG (0.54) POLBDNMT1DNMT3B
SCHEMBL20906737 0.90 POLG (0.54) POLBDNMT1DNMT3B
SCHEMBL22300298 0.90 POLG (0.54) POLBDNMT1DNMT3B
SCHEMBL336251 0.90 POLG (0.54) POLBDNMT1DNMT3B
SCHEMBL15201233 0.90 POLG (0.54) POLBDNMT1DNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8097405-B1 Nucleic acid sequencing processes using non-radioactive detectable modified or labeled nucleotides or nucleotide analogs, and other processes for nucleic acid detection and chromosomal characterization using such non-radioactive detectable modified or labeled nucleotides or nucleotide analogs ENZO BIOCHEM, INC. (US) 2012-01-17 US claimed
US-6992180-B1 Oligo- or polynucleotides comprising phosphate-moiety labeled nucleotides ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) 2006-01-31 US claimed
US-20260125749-A1 HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-05-07 US disclosed
US-12595509-B2 Synthetic nucleic acid spike-ins KARIUS, INC. (US) 2026-04-07 US disclosed
US-20260072019-A1 METHOD OF DETERMINING THE PRESENCE OR ABSENCE OF A TARGET ANALYTE COMPRISING USING A REPORTER POLYNUCLEOTIDE AND A TRANSMEMBRANE PORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-03-12 US disclosed
US-12553085-B2 Sequencing kit OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-02-17 US disclosed
US-20260043809-A1 AFFINITY CAPTURE REAGENTS FOR MASS SPECTROMETRY UNIV OXFORD INNOVATION LTD (GB) 2026-02-12 US disclosed
US-20260028379-A1 MUTANT PORE OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2026-01-29 US disclosed
US-12509721-B2 Methods and systems for characterizing analytes using nanopores OXFORD NANOPORE TECHNOLOGIES PLC (GB) 2025-12-30 US disclosed
EP-4665753-A1 ARMOURED REGULATORY T CELL King's College London (GB) 2025-12-24 EP disclosed
US-20250361502-A1 Promoters And Compositions UNIV OXFORD INNOVATION LTD (GB) 2025-11-27 US disclosed
EP-0618228-A1 Protein with a moiety capable of chelating ions attached thereto ENZO BIOCHEM, INC. (US) 1994-10-05 EP disclosed
US-5260433-A Nonradioactive ENZO DIAGNOSTICS, INC. (US) 1993-11-09 US disclosed
US-5241060-A Base moiety-labeled detectable nucleatide ENZO DIAGNOSTICS, INC. (US) 1993-08-31 US disclosed
EP-0302175-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1989-02-08 EP disclosed
EP-0286898-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1988-10-19 EP disclosed
EP-0285950-A2 A drug delivery conjugate ENZO BIOCHEM, INC. (US) 1988-10-12 EP disclosed
EP-0285058-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1988-10-05 EP disclosed
EP-0097373-A2 Modified labeled nucleotides and polynucleotides and methods of preparing, utilizing and detecting same ENZO BIOCHEM, INC. (US) 1984-01-04 EP disclosed
US-4017606-A CYTOSINE ARABINOSIDE AND HYDROGENATED PYRIMIDINE NUCLEOSIDES THE UPJOHN COMPANY (US) 1977-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260072019-A1 METHOD OF DETERMINING THE PRESENCE OR ABSENCE OF A TARGET ANALYTE COMPRISING USING A REPORTER POLYNUCLEOTIDE AND A TRANSMEMBRANE PORE NUP210, EPCAM, PHAX TYMS 2007/4885POLB 1826/4885DNMT1 2398/4885
US-12509721-B2 Methods and systems for characterizing analytes using nanopores DNA2, MTREX, DDX21 TYMS 997/4885POLB 48/4885DNMT1 123/4885
US-20260043809-A1 AFFINITY CAPTURE REAGENTS FOR MASS SPECTROMETRY DDX6, DDX1, DDB1 TYMS 2902/4885POLB 647/4885DNMT1 679/4885
US-12553085-B2 Sequencing kit PHAX, TIA1, POLM TYMS 1750/4885POLB 684/4885DNMT1 1190/4885
US-20260125749-A1 HAIRPIN LOOP METHOD FOR DOUBLE STRAND POLYNUCLEOTIDE SEQUENCING USING TRANSMEMBRANE PORES POLRMT, PITPNB, NUP205 TYMS 1917/4885POLB 81/4885DNMT1 959/4885
US-20260028379-A1 MUTANT PORE PTMS, NUP50, NUP205 TYMS 3991/4885POLB 2195/4885DNMT1 2912/4885
US-12595509-B2 Synthetic nucleic acid spike-ins SPOUT1, NOP2, METTL16 TYMS 1196/4885POLB 594/4885DNMT1 818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.