Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17205764 | 0.86 | TRPV1 (0.66) | USP2TRPV1HPGDRAB9APOLB | |
| SCHEMBL17205973 | 0.86 | USP2 (0.84) | USP2TRPV1HPGDPOLBMAPT | |
| SCHEMBL17203130 | 0.82 | NPC1 (0.73) | USP2TRPV1HPGDRAB9APOLB | |
| SCHEMBL17205667 | 0.80 | TRPV1 (0.67) | USP2TRPV1HPGDRAB9APOLB | |
| SCHEMBL13438260 | 0.78 | USP2 (0.93) | USP2HPGDPOLBMAPTTSHR | |
| SCHEMBL16610101 | 0.77 | GAA (0.66) | RAB9AMAPTTSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL17205675 | 0.77 | TRPV1 (0.84) | USP2TRPV1HPGDMAPTMEN1 | |
| SCHEMBL17206250 | 0.77 | HPGD (0.75) | USP2TRPV1HPGDRAB9APOLB | |
| SCHEMBL22570479 | 0.76 | USP2 (0.58) | USP2TRPV1RAB9APOLBMAPT | |
| SCHEMBL17205509 | 0.75 | TRPV1 (1.00) | TRPV1HPGDPOLBMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | claimed |
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |