Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17205496 | 0.86 | USP2 (0.62) | TRPV1USP2HPGDRAB9APOLB | |
| SCHEMBL17205973 | 0.86 | USP2 (0.84) | TRPV1USP2HPGDPOLBMEN1 | |
| SCHEMBL17203130 | 0.85 | NPC1 (0.73) | TRPV1USP2HPGDRAB9APOLB | |
| SCHEMBL17205667 | 0.82 | TRPV1 (0.67) | TRPV1USP2HPGDRAB9APOLB | |
| SCHEMBL17205660 | 0.81 | NAMPT (0.65) | TRPV1USP2RAB9APOLBMEN1 | |
| SCHEMBL17205509 | 0.80 | TRPV1 (1.00) | TRPV1HPGDPOLBMEN1KMT2A | |
| SCHEMBL17206250 | 0.79 | HPGD (0.75) | TRPV1USP2HPGDRAB9APOLB | |
| SCHEMBL17205675 | 0.79 | TRPV1 (0.84) | TRPV1USP2HPGDMEN1KMT2A | |
| SCHEMBL26393850 | 0.79 | TRPV1 (1.00) | TRPV1MEN1KMT2ALMNA | |
| SCHEMBL13438260 | 0.78 | USP2 (0.93) | USP2HPGDPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | claimed |
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |