SCHEMBL17205509

SCHEMBL17205509

COc1cc(CNC(=O)CCCc2cccs2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TRPV1 Q8NER1 10/20 1.00
▸ CYP1A2 P05177 4/20 0.64
▸ CYP3A4 P08684 4/20 0.64
▸ CYP2D6 P10635 3/20 0.64
▸ CYP2C9 P11712 3/20 0.64
▸ CYP2C19 P33261 3/20 0.64
▸ ALDH1A1 P00352 3/20 0.64
▸ BLM P54132 2/20 0.64
▸ PMP22 Q01453 2/20 0.64
▸ ALOX15 P16050 2/20 0.64
▸ HPGD P15428 1/20 0.64
▸ ATM Q13315 1/20 0.62
▸ MEN1 O00255 2/20 0.60
▸ KMT2A Q03164 2/20 0.60
▸ POLB P06746 1/20 0.60
▸ TSHR P16473 1/20 0.60
▸ NPSR1 Q6W5P4 1/20 0.60
▸ KDM1A O60341 1/20 0.57
▸ NR1I2 O75469 1/20 0.57
▸ LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17205675 0.91 TRPV1 (0.84) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL17202845 0.86 TRPV1 (0.76) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL17203130 0.83 NPC1 (0.73) TRPV1ALDH1A1HPGDATMPOLB
SCHEMBL5348698 0.82 CYP1A2 (0.90) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL17205697 0.82 TRPV1 (1.00) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL17203305 0.81 TRPV1 (1.00) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL3266072 0.80 HPGD (0.90) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL17205764 0.80 TRPV1 (0.66) TRPV1BLMHPGDMEN1KMT2A
SCHEMBL14034814 0.80 TRPV1 (0.93) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31527869 0.79 CYP1A2 (0.79) TRPV1CYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12390525-B2 Constructs for enhancing immune responses THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) 2025-08-19 — — US claimed
CN-119787997-A Circuit and method for reducing offset voltage of amplifier 广东工业大学 2025-04-08 — — CN claimed
US-20250099421-A1 Analgesic Therapeutics Based on conjugation of Biocompatible Polymers to Ion Channel Modulators Relevium Medical (IE) 2025-03-27 — — US claimed
US-20250032640-A1 TARGETED DRUG DELIVERY-RELEASE AND KILLING OF DRUG RESISTANT TUMORS AND PATHOGENS RUBHU BIOLOGICS INC (US) 2025-01-30 — — US claimed
CN-118761222-A Rapid design method and system for straight pipe welding fixture 中航西安飞机工业集团股份有限公司 2024-10-11 — — CN claimed
CN-117894716-A Process for preventing un-grown epitaxial products from flowing out to next station 杭州中欣晶圆半导体股份有限公司 2024-04-16 — — CN claimed
US-20240082312-A1 COMPOSITIONS AND METHODS FOR WILLIAMS SYNDROME (WS) THERAPY MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2024-03-14 — — US claimed
CN-109963586-B Biological fusion proteins as anti-malarial vaccines 维克芙奥私人有限公司 2023-11-03 — — CN claimed
CN-115785275-B Anti-plasmodium antibody and application thereof 东莞市朋志生物科技有限公司 2023-09-22 — — CN claimed
US-11730769-B2 Compositions and methods for Williams Syndrome (WS) therapy CHILDREN'S MEDICAL CENTER CORPORATION (US) 2023-08-22 — — US claimed
EP-4147715-A1 BIOFUSION PROTEINS AS ANTI-MALARIA VACCINES VAC4all Pte. Ltd. (SG) 2023-03-15 — — EP claimed
CN-115785275-A Anti-plasmodium antibody and application thereof 东莞市朋志生物科技有限公司 2023-03-14 — — CN claimed
US-20220409712-A1 BIOFUSION PROTEINS AS ANTI-MALARIA VACCINES VAC4ALL PTE LTD (SG) 2022-12-29 — — US claimed
WO-2022222352-A1 REMOTE-SENSING PANCHROMATIC AND MULTISPECTRAL IMAGE DISTRIBUTED FUSION METHOD BASED ON RESIDUAL NETWORK 海南大学 2022-10-27 — — WO claimed
US-20220331423-A1 Constructs for Enhancing Immune Responses NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-10-20 — — US claimed
CN-114785114-A High-voltage transformation ratio mixed mode two-phase power converter 电子科技大学 2022-07-22 — — CN claimed
EP-3487526-B1 BIOFUSION PROTEINS AS ANTI-MALARIA VACCINES VAC4ALL PTE LTD (SG) 2022-07-06 — — EP claimed
CN-112775937-B Self-adaptive robust control method and device for under-actuated hydraulic single-leg power-assisted exoskeleton 合肥工业大学 2022-04-29 — — CN claimed
CN-112388616-B Adaptive robust force control method and device for under-actuated support leg assistance exoskeleton 合肥工业大学 2022-02-22 — — CN claimed
WO-2015162216-A1 BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS UNIVERSITA' DEGLI STUDI DI SIENA (IT) 2015-10-29 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730769-B2 Compositions and methods for Williams Syndrome (WS) therapy MAG, PMP22, WDR77 TRPV1 4573/4885CYP1A2 4855/4885CYP3A4 4885/4885
US-20240082312-A1 COMPOSITIONS AND METHODS FOR WILLIAMS SYNDROME (WS) THERAPY MAG, PMP22, WDR77 TRPV1 4573/4885CYP1A2 4855/4885CYP3A4 4885/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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