Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720744 | 0.87 | KIF11 (0.63) | KIF11CYP11B1CYP11B2PRSS1ACR | |
| SCHEMBL10708473 | 0.86 | MAPT (0.50) | PRSS1ACRMEN1KMT2AALDH1A1 | |
| SCHEMBL10708455 | 0.84 | KIF11 (0.56) | KIF11CYP11B1CYP11B2PRSS1ACR | |
| SCHEMBL10706875 | 0.82 | KIF11 (0.54) | KIF11CYP11B1CYP11B2PRSS1ACR | |
| SCHEMBL10706859 | 0.82 | KIF11 (0.54) | KIF11CYP11B1CYP11B2PRSS1ACR | |
| SCHEMBL10710114 | 0.82 | KMT2A (0.46) | CES2CES1MAOBMEN1KMT2A | |
| SCHEMBL10707280 | 0.80 | CES2 (0.45) | CES2CES1MEN1KMT2AALDH1A1 | |
| SCHEMBL697018 | 0.80 | KIF11 (0.56) | KIF11CYP11B1CYP11B2PRSS1ACR | |
| SCHEMBL10710711 | 0.80 | LMNA (0.53) | PRSS1ACRMEN1KMT2AALDH1A1 | |
| SCHEMBL1401602 | 0.78 | MAPT (0.43) | MEN1KMT2AALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184012-B1 | LIQUID CRYSTAL COMPOSITIONS | BAYER AG (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0184012-A1 | Liquid crystal compositions | BAYER AG (DE) | 1986-06-11 | — | — | EP | disclosed |