Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415465 | 0.87 | MAPT (0.56) | MAPTCHRM3CHRM2CHRM1HDAC1 | |
| SCHEMBL3906763 | 0.87 | MAPT (0.56) | MAPTCHRM3CHRM2CHRM1HDAC1 | |
| SCHEMBL2479383 | 0.84 | ADORA3 (0.53) | MAPTTOP2ASMN1; SMN2GAANPC1 | |
| SCHEMBL1116494 | 0.84 | CHRM3 (0.53) | MAPTCHRM3CHRM2CHRM1KDM4E | |
| SCHEMBL17805491 | 0.84 | CHRM3 (0.61) | MAPTCHRM3CHRM2CHRM1 | |
| SCHEMBL20194476 | 0.83 | HDAC1 (0.66) | MAPTHDAC1KDM4EAPOBEC3AGFER | |
| SCHEMBL20194441 | 0.83 | MAPT (0.56) | MAPTCHRM3CHRM2CHRM1RAB9A | |
| SCHEMBL11187279 | 0.82 | HDAC7 (0.54) | MAPTCHRM3HDAC1KDM4EAPOBEC3A | |
| SCHEMBL17206261 | 0.82 | KDM4E (0.55) | MAPTHDAC1KDM4EAPOBEC3AGFER | |
| SCHEMBL17206020 | 0.81 | CHRM3 (0.52) | MAPTCHRM3CHRM2CHRM1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10246407-B2 | Process for preparing biphenylamines from anilides by ruthenium catalysis | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-02 | — | — | US | disclosed |
| US-10246408-B2 | Process for preparing biphenylamines from anilides by ruthenium catalysis | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-04-02 | — | — | US | disclosed |
| EP-3326715-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2018-05-30 | — | — | EP | disclosed |
| US-20170044094-A1 | PROCESS FOR PREPARING BIPHENYLAMINES FROM ANILIDES BY RUTHENIUM CATALYSIS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | US | disclosed |
| US-20170044094-A1 | PROCESS FOR PREPARING BIPHENYLAMINES FROM ANILIDES BY RUTHENIUM CATALYSIS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2017-02-16 | — | — | US | disclosed |
| EP-3009420-A1 | Method for the production of biphenylamines from anilides using ruthenium catalysis | Bayer CropScience AG (DE) | 2016-04-20 | — | — | EP | disclosed |
| WO-2015162144-A1 | METHOD FOR PRODUCING BIPHENYLAMINES FROM ANILIDES BY RUTHENIUM CATALYSIS | BAYER CROPSCIENCE AG (DE) | 2015-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10246407-B2 | Process for preparing biphenylamines from anilides by ruthenium catalysis | SBDS, AGPS, CYP2B6 | MAPT 3447/4885CHRM3 2865/4885CHRM2 2183/4885 |
| US-10246408-B2 | Process for preparing biphenylamines from anilides by ruthenium catalysis | SBDS, AGPS, CYP2B6 | MAPT 3447/4885CHRM3 2865/4885CHRM2 2183/4885 |
| US-20170044094-A1 | PROCESS FOR PREPARING BIPHENYLAMINES FROM ANILIDES BY RUTHENIUM CATALYSIS | SBDS, AGPS, CYP2B6 | MAPT 3447/4885CHRM3 2865/4885CHRM2 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.