Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.66 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.66 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.51 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18415445 | 0.86 | PTPN1 (0.58) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL17206261 | 0.85 | KDM4E (0.55) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL11187279 | 0.85 | HDAC7 (0.54) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL18582710 | 0.83 | HDAC1 (0.50) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL21244213 | 0.83 | KDM4E (0.64) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL17209129 | 0.83 | MAPT (0.54) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL30307389 | 0.83 | ALDH1A1 (0.56) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL99089 | 0.83 | ALDH1A1 (0.56) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL99181 | 0.82 | ALDH1A1 (0.59) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G | |
| SCHEMBL18582879 | 0.82 | HDAC1 (0.52) | HDAC1KDM4EAPOBEC3AGFERAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3326715-A1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2018-05-30 | — | — | EP | disclosed |