Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18539062 | 0.94 | TRPA1 (0.43) | TRPA1ATML3MBTL1RXFP1CYP1A2 | |
| SCHEMBL17201953 | 0.89 | TRPA1 (0.50) | TRPA1ATML3MBTL1RXFP1CYP1A2 | |
| SCHEMBL17202229 | 0.87 | TRPA1 (0.41) | TRPA1ATML3MBTL1RXFP1CYP1A2 | |
| SCHEMBL17210373 | 0.85 | ALDH1A1 (0.42) | TRPA1ATML3MBTL1RXFP1CYP1A2 | |
| SCHEMBL17205297 | 0.83 | TRPA1 (0.41) | TRPA1ATML3MBTL1RXFP1CYP1A2 | |
| SCHEMBL17205151 | 0.81 | TRPA1 (0.44) | TRPA1ATML3MBTL1RXFP1CYP1A2 | |
| SCHEMBL17205350 | 0.81 | TRPA1 (0.44) | TRPA1ATML3MBTL1RXFP1CYP1A2 | |
| SCHEMBL17204914 | 0.81 | MAP3K12 (0.40) | TRPA1ATML3MBTL1RXFP1CYP1A2 | |
| SCHEMBL17204949 | 0.81 | TRPA1 (0.42) | TRPA1ATML3MBTL1RXFP1CYP1A2 | |
| SCHEMBL17210406 | 0.77 | ATM (0.45) | ATML3MBTL1RXFP1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015164643-A1 | INHIBITING THE TRANSIENT RECEPTOR POTENTIAL A1 ION CHANNEL | HYDRA BIOSCIENCES, INC. (US) | 2015-10-29 | — | — | WO | disclosed |