Sugi Predict

Sugi Predict / Compounds / SCHEMBL17210993

SCHEMBL17210993

SCHEMBL17210993

Cc1cn([C@@H]2O[C@H](COP(=O)(Cl)Cl)[C@H](O)C2O)c(=O)nc1N

nearest known ligand 0.76

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 6/20 0.50
▸ P2RY6 Q15077 5/20 0.49
▸ TSHR P16473 1/20 0.47
▸ GLA P06280 1/20 0.47
▸ P2RY4 P51582 1/20 0.46
▸ FBP1 P09467 1/20 0.46
▸ ATIC P31939 1/20 0.46
▸ CA5A P35218 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16805400 1.00 P2RY2 (0.50) P2RY2P2RY6TSHRGLAP2RY4
SCHEMBL18289616 0.93 P2RY2 (0.48) P2RY2P2RY6TSHRGLAP2RY4
SCHEMBL16805294 0.91 P2RY2 (0.47) P2RY2P2RY6TSHRGLAP2RY4
SCHEMBL14946157 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4FBP1ATIC
SCHEMBL16489878 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4FBP1ATIC
SCHEMBL17809090 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4FBP1ATIC
SCHEMBL17789100 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4FBP1ATIC
SCHEMBL903054 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4FBP1ATIC
SCHEMBL3504116 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4FBP1ATIC
SCHEMBL3504106 0.90 FBP1 (0.57) P2RY2P2RY6P2RY4FBP1ATIC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2017-06-22 — — US disclosed
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF Modema Therapeutics, Inc. (US) 2017-05-18 — — US disclosed
US-20170136132-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. (US) 2017-05-18 — — US disclosed
US-20160354491-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS INC (US) 2016-12-08 — — US disclosed
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC. 2016-10-20 — — US disclosed
US-20150307542-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX, INC. 2015-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304552-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 P2RY2 2899/4885P2RY6 1545/4885TSHR 2428/4885
US-20170136132-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 P2RY2 2786/4885P2RY6 2112/4885TSHR 3169/4885
US-20160354491-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 P2RY2 2899/4885P2RY6 1545/4885TSHR 2428/4885
US-20170175129-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 P2RY2 2786/4885P2RY6 2112/4885TSHR 3169/4885
US-20170136131-A1 ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, RNGTT, NSUN3 P2RY2 2786/4885P2RY6 2112/4885TSHR 3169/4885
US-20150307542-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 P2RY2 2899/4885P2RY6 1545/4885TSHR 2428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.