Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720864 | 0.88 | ADORA2B (0.43) | ADORA2BADORA1GPR34MAOBMAOA | |
| SCHEMBL2685011 | 0.79 | ADORA1 (0.58) | ADORA2BADORA1 | |
| SCHEMBL30891856 | 0.79 | ADORA1 (0.58) | ADORA2BADORA1 | |
| SCHEMBL2686035 | 0.78 | ADORA1 (0.43) | ADORA2BADORA1GPR34MAOBMAOA | |
| SCHEMBL1721091 | 0.75 | ADORA1 (0.43) | ADORA2BADORA1MAOAPPARDALDH1A1 | |
| SCHEMBL1721383 | 0.71 | ADORA2B (0.37) | ADORA2BADORA1 | |
| SCHEMBL11435944 | 0.69 | GSTP1 (0.50) | GPR34MAOBPPARDNR4A2 | |
| SCHEMBL30891822 | 0.66 | ADORA1 (0.63) | ADORA2BADORA1 | |
| SCHEMBL2684084 | 0.66 | ADORA1 (0.63) | ADORA2BADORA1 | |
| SCHEMBL1946830 | 0.65 | ADORA2B (0.62) | ADORA2BADORA1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2405917-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | Advinus Therapeutics Private Limited (IN) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103547-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2010-09-16 | — | — | WO | disclosed |