Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721091 | 0.88 | ADORA1 (0.43) | ADORA2BADORA1PPARDALDH1A1HPGD | |
| SCHEMBL1721175 | 0.88 | ADORA2B (0.44) | ADORA2BGPR34ADORA1PPARDALDH1A1 | |
| SCHEMBL1721383 | 0.83 | ADORA2B (0.37) | ADORA2BADORA1MAPT | |
| SCHEMBL30891856 | 0.76 | ADORA1 (0.58) | ADORA2BADORA1 | |
| SCHEMBL2685011 | 0.76 | ADORA1 (0.58) | ADORA2BADORA1 | |
| SCHEMBL2686035 | 0.75 | ADORA1 (0.43) | ADORA2BGPR34ADORA1PPARDALDH1A1 | |
| SCHEMBL1720580 | 0.70 | SCD (0.38) | ADORA2BADORA1 | |
| SCHEMBL11435944 | 0.69 | GSTP1 (0.50) | GPR34PPARDNR4A2FFAR1MAOB | |
| SCHEMBL1865267 | 0.68 | ADORA1 (0.44) | ADORA2BADORA1ALDH1A1MAOBMAOA | |
| SCHEMBL1946830 | 0.64 | ADORA2B (0.62) | ADORA2BADORA1ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727391-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER | Impetis Biosciences Ltd. (IN) | 2020-10-28 | — | — | EP | claimed |
| EP-3727391-A1 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF CANCER | Impetis Biosciences Ltd. (IN) | 2020-10-28 | — | — | EP | disclosed |
| EP-2405917-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | Advinus Therapeutics Private Limited (IN) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103547-A2 | SUBSTITUTED FUSED PYRIMIDINE COMPOUNDS | ADVINUS THERAPEUTICS PRIVATE LIMITED (IN) | 2010-09-16 | — | — | WO | disclosed |