Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.66 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.66 |
| ▸ | TSHR | P16473 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 14/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18023028 | 0.89 | CYP1A2 (0.58) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL14727535 | 0.88 | CYP1A2 (0.65) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL14474077 | 0.88 | CYP1A2 (0.65) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL14475165 | 0.86 | CYP1A2 (0.62) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL14474995 | 0.85 | ALDH1A1 (0.61) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL14727590 | 0.84 | CYP1A2 (0.59) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL14474989 | 0.83 | CYP1A2 (0.58) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL14474581 | 0.82 | CYP3A4 (0.66) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL14475027 | 0.81 | CYP1A2 (0.65) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL14474975 | 0.81 | MEN1 (0.65) | CYP1A2CYP2D6CLK4TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170217923-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
| US-20150307477-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | GALENEA CORPORATION | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307477-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PTPRG, PPP2CA | CYP1A2 4552/4885CYP2D6 4717/4885CLK4 2170/4885 |
| US-20170217923-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PTPRG, PPP2CA | CYP1A2 4552/4885CYP2D6 4717/4885CLK4 2170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.