Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11720340 | 0.76 | LMNA (0.40) | LMNAMAPTHSD17B10ADORA2BSMN1; SMN2 | |
| SCHEMBL11718868 | 0.69 | BRD4 (0.38) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL11720948 | 0.67 | MEN1 (0.43) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL11715063 | 0.67 | MEN1 (0.40) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL14968971 | 0.67 | LMNA (0.46) | LMNAMEN1KMT2AABCC4PKM | |
| SCHEMBL24173791 | 0.65 | LMNA (0.33) | LMNAMAPTADORA2B | |
| SCHEMBL24174689 | 0.63 | LMNA (0.32) | LMNAMAPT | |
| SCHEMBL7597448 | 0.63 | ADORA2B (0.49) | LMNAMEN1KMT2APKMMAPT | |
| SCHEMBL2357119 | 0.63 | BRD4 (0.37) | LMNAKMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL22678925 | 0.63 | MAPK1 (0.39) | LMNAMAPTHSD17B10SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137625-A1 | SELF-ASSEMBLY OF DNA ORIGAMI: A NEW DIAGNOSTIC TOOL | Baseclick GmbH (DE) | 2017-03-08 | — | — | EP | disclosed |
| US-20170051338-A1 | SELF-ASSEMBLY OF DNA ORIGAMI: A NEW DIAGNOSTIC TOOL | BASECLICK GMBH (DE) | 2017-02-23 | — | — | US | disclosed |
| WO-2015165643-A1 | SELF-ASSEMBLY OF DNA ORIGAMI: A NEW DIAGNOSTIC TOOL | BASECLICK GMBH (DE) | 2015-11-05 | — | — | WO | disclosed |
| EP-2940150-A1 | Self-assembly of DNA Origami: a new diganostic tool | Baseclick GmbH (DE) | 2015-11-04 | — | — | EP | disclosed |