SCHEMBL7597448

SCHEMBL7597448

Cc1cn(CC(=O)O)c(=O)n(C)c1=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA2B P29275 2/20 0.49
LMNA P02545 2/20 0.49
KDM4E B2RXH2 4/20 0.46
ALDH1A1 P00352 4/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIA1 P42261 1/20 0.36
GRIA2 P42262 1/20 0.36
GRIA3 P42263 1/20 0.36
GRIA4 P48058 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17870740 0.81 ADORA2B (0.48) ADORA2BLMNAKDM4EALDH1A1POLB
SCHEMBL3930330 0.81 KDM4E (0.45) ADORA2BLMNAKDM4EALDH1A1POLB
SCHEMBL24666582 0.79 KDM4E (0.44) ADORA2BLMNAKDM4EALDH1A1POLB
SCHEMBL25980045 0.78 LMNA (0.46) ADORA2BLMNAKDM4EALDH1A1POLB
SCHEMBL27386680 0.78 GRIN2D (0.40) ADORA2BLMNAKDM4EALDH1A1POLB
SCHEMBL24665501 0.77 ALDH1A1 (0.39) ADORA2BLMNAKDM4EALDH1A1POLB
SCHEMBL15125556 0.77 DRD2 (0.43) ADORA2BLMNAKDM4EALDH1A1POLB
SCHEMBL17870783 0.76 KDM4E (0.38) ADORA2BLMNAKDM4EALDH1A1POLB
SCHEMBL22511462 0.75 ADORA2B (0.49) ADORA2BLMNAKDM4EALDH1A1KMT2A
SCHEMBL19873718 0.75 LMNA (0.38) ADORA2BLMNAKDM4EALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020025401-A1 Optical storage using materials comprising chromophore oligomers which can undergo cycloaddition OPTILINK AB (SE) 2002-02-28 US disclosed