SCHEMBL17216

SCHEMBL17216

O=C(c1ccc(Br)cc1)C(F)(F)F

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.60
CES2 O00748 1/20 0.54
MLYCD O95822 8/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
LMNA P02545 1/20 0.47
HSP90AA1 P07900 1/20 0.47
MAPT P10636 1/20 0.47
HTT P42858 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
GSK3B P49841 2/20 0.46
TRPV1 Q8NER1 1/20 0.46
OGG1 O15527 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5014652 0.88 CES1 (0.48) CES1CES2MLYCDCA1CA2
SCHEMBL29035984 0.86 CES1 (0.54) CES1CES2CA1CA2LMNA
SCHEMBL29137293 0.86 CES1 (0.54) CES1CES2CA1CA2LMNA
SCHEMBL20640032 0.84 MLYCD (0.50) CES1MLYCDCA2LMNAHSP90AA1
SCHEMBL4490669 0.82 CES1 (0.43) CES1CES2MLYCDCA1CA2
SCHEMBL4656447 0.82 CES2 (0.62) CES1CES2CA1CA2LMNA
SCHEMBL28906999 0.82 CES1 (0.50) CES1CES2CA1CA2LMNA
SCHEMBL7958861 0.82 CES1 (0.50) CES1CES2CA1CA2LMNA
SCHEMBL19056956 0.80 CES1 (0.65) CES1MLYCDTRPV1
SCHEMBL2174033 0.78 CES1 (0.62) CES1CES2MLYCDCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 676 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4581071-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2025-07-09 EP claimed
US-12247233-B2 Transaminase reactions CODEXIS, INC. (US) 2025-03-11 US claimed
CN-113462728-B Method for preparing (R) -1- (4-bromophenyl) -2, 2-trifluoroethanol by using starwheel head yeast 浙江工业大学 2024-06-07 CN claimed
CN-118002201-A Supported cluster catalyst and application thereof in ketynyl reaction 安徽大学 2024-05-10 CN claimed
WO-2024046712-A1 METHOD FOR PRODUCING A MATERIAL FOR A MEMBRANE, MATERIAL, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-03-07 WO claimed
CN-117334974-A Polyfluoro side chain anion exchange membrane for direct ammonia fuel cell and preparation method thereof 中国科学院大连化学物理研究所 2024-01-02 CN claimed
CN-116970580-A Short-chain dehydrogenase mutant derived from Raffina and application of short-chain dehydrogenase mutant in catalyzing aryl ketone to prepare chiral alcohol 浙江工业大学 2023-10-31 CN claimed
CN-116813957-A Separator, preparation method and application thereof 宁波中科氢易膜科技有限公司 2023-09-29 CN claimed
CN-116064688-A Application of Curvularia longifolia ZJPH2105 in preparation of chiral aromatic alcohol through biocatalysis 浙江工业大学 2023-05-05 CN claimed
CN-108250109-B Synthesis method of substituted biphenyl compound 苏州科伦药物研究有限公司 2023-03-07 CN claimed
EP-2446026-B1 TRANSAMINASE REACTIONS CODEXIS INC (US) 2017-08-09 EP claimed
US-9434968-B2 Transaminase reactions CODEXIS, INC. (US) 2016-09-06 US claimed
CN-105175583-A Acetophenone photoinitiator with biphenyl as conjugate structure, preparation method and application thereof UNIV TONGJI 2015-12-23 CN claimed
CN-105153329-A Acetophenone type photoinitiators using fluorene as conjugated structure as well as preparation method and application of acetophenone type photoinitiators UNIV TONGJI 2015-12-16 CN claimed
CN-102597226-B Transamination reaction CODEXIS, INC. (US) 2015-08-19 CN claimed
US-20150079640-A1 TRANSAMINASE REACTIONS INNOVATUS LIFE SCIENCES LENDING FUND I, LP, AS COLLATERAL AGENT 2015-03-19 US claimed
US-8921079-B2 Transaminase reactions CODEXIS, INC. (US) 2014-12-30 US claimed
US-20120190085-A1 Transaminase Reactions CODEXIS, INC. (US) 2012-07-26 US claimed
EP-2446026-A1 TRANSAMINASE REACTIONS Codexis, Inc. (US) 2012-05-02 EP claimed
WO-2011005477-A1 TRANSAMINASE REACTIONS CODEXIS, INC. (US) 2011-01-13 WO claimed