Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | MLYCD | O95822 | 10/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | OGG1 | O15527 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17216 | 0.82 | CES1 (0.60) | CES1MLYCDCES2LMNAHSP90AA1 | |
| SCHEMBL4509253 | 0.82 | HTR2A (0.39) | CA1CA2DPP4DPP7 | |
| SCHEMBL1048801 | 0.82 | HTR2A (0.39) | CA1CA2DPP4DPP7 | |
| SCHEMBL1050341 | 0.82 | HTR2A (0.39) | CA1CA2DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL1864740 | 0.80 | HTR2A (0.38) | CA1CA2DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL4513936 | 0.80 | HTR2A (0.38) | CA1CA2DPP4DPP7 | |
| Hydrochloric Acid SCHEMBL16653694 | 0.80 | HTR2A (0.38) | CA1CA2DPP4DPP7 | |
| SCHEMBL20768664 | 0.75 | ANPEP (0.52) | CA1CA2 | |
| SCHEMBL5014652 | 0.73 | CES1 (0.48) | CES1MLYCDCES2LMNAHSP90AA1 | |
| SCHEMBL19331703 | 0.71 | DPP4 (0.51) | MEN1KMT2AMAPTHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291988-A1 | Reversible Inhibitors of Monoamine Oxidase A and B | MERCK FROSST CANADA LTD. (CA) | 2009-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291988-A1 | Reversible Inhibitors of Monoamine Oxidase A and B | MAOB, MAOA, XDH | CES1 512/4885MLYCD 233/4885MEN1 2309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.